MARC details
| 000 -LÍDER |
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| fixed length control field |
03081cam a2200301 a 4500 |
| 001 - NÚMERO DE CONTROL |
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| control field |
u317915 |
| 003 - IDENTIFICADOR DEL NÚMERO DE CONTROL |
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| control field |
SIRSI |
| 005 - FECHA Y HORA DE LA ULTIMA TRANSACCIÓN |
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| control field |
20160811212106.0 |
| 008 - ELEMENTOS DE LONGITUD FIJA -- INFORMACIÓN GENERAL |
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| fixed length control field |
081027s2009 sz ad fr 000 0 eng d |
| 020 ## - NÚMERO INTERNACIONAL NORMALIZADO PARA LIBROS |
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| International Standard Book Number |
9789241572392 |
| 020 ## - NÚMERO INTERNACIONAL NORMALIZADO PARA LIBROS |
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| International Standard Book Number |
9241572396 |
| 040 ## - FUENTE DE CATALOGACIÓN |
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| Transcribing agency |
MX-MeUAM |
| 050 #0 - SIGNATURA TOPOGRÁFICA DE LA BIBLIOTECA DEL CONGRESO |
|---|
| Classification number |
RM301.8 |
| Item number |
P75 2009 |
| 245 00 - MENCIÓN DE TITULO |
|---|
| Title |
Principles for modelling dose-response for the risk assessment of chemicals / |
| Statement of responsibility, etc. |
first draft prepared by the WHO Task Group on Environmental Health Criteria on Principles for Modelling Dose-Response for the Risk Assessment of Chemicals. |
| 260 ## - PUBLICACIÓN, DISTRIBUCIÓN, ETC. (PIE DE IMPRENTA) |
|---|
| Place of publication, distribution, etc. |
Geneva, Switzerland : |
| Name of publisher, distributor, etc. |
World Health Organization, |
| Date of publication, distribution, etc. |
c2009. |
| 300 ## - DESCRIPCIÓN FÍSICA |
|---|
| Extent |
xx, 137 p. : |
| Other physical details |
il., gráficos ; |
| Dimensions |
21 cm. |
| 490 1# - MENCIÓN DE SERIE |
|---|
| Series statement |
Environmental health criteria, |
| International Standard Serial Number |
0250-863X ; |
| Volume/sequential designation |
239 |
| 520 3# - NOTA DE RESUMEN, ETC. |
|---|
| Summary, etc. |
This volume is part of the ongoing review of the underlying scientific bases for decision-making in chemical risk assessment by International Program on Chemical Safety. It involves specific consideration of the area of dose-response assessment in the evaluation of information from toxicological studies in animals and from human clinical and epidemiological studies. It covers toxicants with threshold effects and those for which there may be no practical threshold, such as substances that are genotoxic and carcinogenic. The discussions are concerned with that subset of cause-effect relationships commonly referred to as dose-response models, which are typically used to characterize the biological effects of intentional (e.g. drugs and nutrients) and unintentional (e.g. contaminants) exposure to chemicals. This report is intended primarily to provide descriptive guidance for risk assessors in using dose-response modeling in hazard characterization. It will also provide mathematical modelers with an appreciation of issues to be considered when modeling in the context of the risk assessment process. Risk managers will be able to obtain a general understanding of the applications and limitations of dose-response modeling. For both risk assessors and risk managers, some considerations for communicating the results of risk assessments that use dose-response modeling are presented.--Publisher's description. |
| 505 2# - NOTA DE CONTENIDO |
|---|
| Formatted contents note |
Summary, conclusions, and recommendations -- Introduction -- Risk analysis -- Dose-response modelling : basic concepts -- Dose-response modelling : why and when to use it -- Principles of dose-response modelling -- Communicating the results of dose-response modelling -- Conclusions and recommendations. |
| 500 ## - NOTA GENERAL |
|---|
| General note |
"Published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organisation and the World Health Organization, and produced within the framework of the Inter-Organization Programme for the Sound Management of Chemicals." |
| 504 ## - NOTA DE BIBLIOGRAFÍA, ETC. |
|---|
| Bibliography, etc |
Incluye referencias bibliográficas (p. 103-110). |
| 596 ## - |
|---|
| -- |
4 12 |
| 650 #7 - ASIENTO SECUNDARIO DE MATERIA - TERMINO TEMÁTICO |
|---|
| Topical term or geographic name as entry element |
Drogas |
| General subdivision |
Relación-dosis-respuesta. |
| Source of heading or term |
lemb |
| 710 2# - ASIENTO SECUNDARIO - NOMBRE CORPORATIVO |
|---|
| Corporate name or jurisdiction name as entry element |
World Health Organization. |
| 830 #0 - ASIENTO SECUNDARIO DE SERIE--TITULO UNIFORME |
|---|
| Uniform title |
Environmental health criteria ; |
| Volume number/sequential designation |
239. |
| 942 ## - TIPO DE MATERIAL (KOHA) |
|---|
| Koha item type |
Libro |
