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110110s2010 xxu| s |||| 0|eng d |
| 020 ## - NÚMERO INTERNACIONAL NORMALIZADO PARA LIBROS |
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| International Standard Book Number |
9781441963543 |
| -- |
978-1-4419-6354-3 |
| 040 ## - FUENTE DE CATALOGACIÓN |
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| Transcribing agency |
MX-MeUAM |
| 050 #4 - SIGNATURA TOPOGRÁFICA DE LA BIBLIOTECA DEL CONGRESO |
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| Classification number |
R-RZ |
| 082 04 - NÚMERO DE CLASIFICACIÓN DECIMAL DEWEY |
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| Classification number |
610 |
| Edition number |
23 |
| 100 1# - ASIENTO PRINCIPAL--NOMBRE PERSONAL |
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| Personal name |
Catania, Anna. |
| Relator term |
editor. |
| 245 10 - MENCIÓN DE TITULO |
|---|
| Title |
Melanocortins: Multiple Actions and Therapeutic Potential |
| Medium |
[recurso electrónico] / |
| Statement of responsibility, etc. |
edited by Anna Catania. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
New York, NY : |
| Name of producer, publisher, distributor, manufacturer |
Springer New York, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2010. |
| 300 ## - DESCRIPCIÓN FÍSICA |
|---|
| Extent |
XX, 153 p. |
| Other physical details |
online resource. |
| 336 ## - CONTENT TYPE |
|---|
| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
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| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
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| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
|---|
| File type |
text file |
| Encoding format |
PDF |
| Source |
rda |
| 490 1# - MENCIÓN DE SERIE |
|---|
| Series statement |
Advances in Experimental Medicine and Biology, |
| International Standard Serial Number |
0065-2598 ; |
| Volume/sequential designation |
681 |
| 505 0# - NOTA DE CONTENIDO |
|---|
| Formatted contents note |
Structure-Activity Relationships (SAR) of Melanocortin and Agouti-Related (AGRP) Peptides -- Melanocortin Signalling Mechanisms -- Distribution and Function of Melanocortin Receptors within the Brain -- Drugs, Exercise, and the Melanocortin-4 Receptor— Different Means, Same Ends: Treating Obesity -- Melanocortins in Brain Inflammation: The Role of Melanocortin Receptor Subtypes -- Melanocortins and the Cholinergic Anti-Inflammatory Pathway -- Melanocortin Control of Cell Trafficking in Vascular Inflammation -- Terminal Signal: Anti-Inflammatory Effects of ?-Melanocyte-Stimulating Hormone Related Peptides Beyond the Pharmacophore -- Protective Effects of Melanocortins in Systemic Host Reactions -- Development of ?-Melanocortin Analogs for Melanoma Prevention and Targeting -- MSH Radiopeptides for Targeting Melanoma Metastases -- Applications of the Role of ?-MSH in Ocular Immune Privilege. |
| 520 ## - NOTA DE RESUMEN, ETC. |
|---|
| Summary, etc. |
It is clear that the melanocortins are of immense academic interest. Further, these molecules have remarkable potential as pharmaceutical agents for treatment of multiple human and veterinary disorders and diseases. The evidence to support academic interest and clinical applications lies in significant part within the chapters of this book, chapters written by noted experts in the field who have worked diligently to understand the molecules and to move them toward clinical applications. I personally believe that the - MSH molecule and its derivatives will be used as routine therapeutics in the very near future. My belief is so strong that I left academia to form a company based on -MSH analogs and have caused millions of dollars to be spent on melanocortin research. Now why would a sane professor pick up such a challenge and enter business, an essential step toward any clinical application? It is the - MSH story that drove me. Consider that - MSH occurs in exactly the same amino acid sequence in humans and in the sea lamprey, an organism unchanged since its appearance during the Pennsylvanian period of the Paleozoic era (about 300 million years ago—way before dinosaurs were to be considered). There is unpublished evidence that the stability of the molecule can be traced back a half billion years. Frankly, I believe that the molecule existed even when single cells began to live together. |
| 596 ## - |
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| -- |
19 |
| 650 #0 - ASIENTO SECUNDARIO DE MATERIA - TERMINO TEMÁTICO |
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| Topical term or geographic name as entry element |
Medicine. |
| 650 14 - ASIENTO SECUNDARIO DE MATERIA - TERMINO TEMÁTICO |
|---|
| Topical term or geographic name as entry element |
Biomedicine. |
| 650 24 - ASIENTO SECUNDARIO DE MATERIA - TERMINO TEMÁTICO |
|---|
| Topical term or geographic name as entry element |
Biomedicine general. |
| 710 2# - ASIENTO SECUNDARIO - NOMBRE CORPORATIVO |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Relationship information |
Printed edition: |
| International Standard Book Number |
9781441963536 |
| 830 #0 - ASIENTO SECUNDARIO DE SERIE--TITULO UNIFORME |
|---|
| Uniform title |
Advances in Experimental Medicine and Biology, |
| International Standard Serial Number |
0065-2598 ; |
| Volume number/sequential designation |
681 |
| 856 40 - LOCALIZACIÓN Y ACCESO ELECTRÓNICOS |
|---|
| Public note |
Libro electrónico |
| Uniform Resource Identifier |
<a href="http://148.231.10.114:2048/login?url=http://link.springer.com/book/10.1007/978-1-4419-6354-3">http://148.231.10.114:2048/login?url=http://link.springer.com/book/10.1007/978-1-4419-6354-3</a> |
| 942 ## - TIPO DE MATERIAL (KOHA) |
|---|
| Koha item type |
Libro Electrónico |
