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| 001 - NÚMERO DE CONTROL |
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SIRSI |
| 005 - FECHA Y HORA DE LA ULTIMA TRANSACCIÓN |
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20160812084145.0 |
| 007 - CAMPO FIJO DE DESCRIPCIÓN FIJA--INFORMACIÓN GENERAL |
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| 008 - ELEMENTOS DE LONGITUD FIJA -- INFORMACIÓN GENERAL |
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100301s2010 gw | s |||| 0|eng d |
| 020 ## - NÚMERO INTERNACIONAL NORMALIZADO PARA LIBROS |
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| International Standard Book Number |
9783642021121 |
| -- |
978-3-642-02112-1 |
| 040 ## - FUENTE DE CATALOGACIÓN |
|---|
| Transcribing agency |
MX-MeUAM |
| 050 #4 - SIGNATURA TOPOGRÁFICA DE LA BIBLIOTECA DEL CONGRESO |
|---|
| Classification number |
QH573-671 |
| 082 04 - NÚMERO DE CLASIFICACIÓN DECIMAL DEWEY |
|---|
| Classification number |
571.6 |
| Edition number |
23 |
| 100 1# - ASIENTO PRINCIPAL--NOMBRE PERSONAL |
|---|
| Personal name |
Sitaramayya, Ari. |
| Relator term |
editor. |
| 245 10 - MENCIÓN DE TITULO |
|---|
| Title |
Signal Transduction: Pathways, Mechanisms and Diseases |
| Medium |
[recurso electrónico] / |
| Statement of responsibility, etc. |
edited by Ari Sitaramayya. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
Berlin, Heidelberg : |
| Name of producer, publisher, distributor, manufacturer |
Springer Berlin Heidelberg, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2010. |
| 300 ## - DESCRIPCIÓN FÍSICA |
|---|
| Extent |
XI, 437 p. |
| Other physical details |
online resource. |
| 336 ## - CONTENT TYPE |
|---|
| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
|---|
| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
|---|
| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
|---|
| File type |
text file |
| Encoding format |
PDF |
| Source |
rda |
| 505 0# - NOTA DE CONTENIDO |
|---|
| Formatted contents note |
G Proteins and G Protein–Coupled Receptors -- Traditional GPCR Pharmacology and Beyond -- Regulation of Intraneuronal Trafficking of G-Protein-Coupled Receptors by Neurotransmitters In Vivo -- Small GTPases and Their Role in Regulating G Protein-Coupled Receptor Signal Transduction -- Regulation of G Protein Receptor Coupling, Mood Disorders and Mechanism of Action of Antidepressants -- Dysregulation of G Protein-Coupled Receptor Signaling in Cancer -- Growth Factors -- Insulin Signaling in Normal and Diabetic Conditions -- Epidermal Growth Factor (EGF) Receptor Signaling and Cancer -- Leptin Signaling Pathway -- Signaling in Normal and Pathological Angiogenesis -- Signaling Platforms -- Spatial and Temporal Control of Cell Signaling by A-Kinase Anchoring Proteins -- Mitochondria, a Platform for Diverse Signaling Pathways -- Mitogen-Activated Protein Kinases and Their Scaffolding Proteins -- Molecular and Functional Determinants of Ca2+ Signaling Microdomains -- Nuclear Receptors / Transcription -- Eukaryotic Gene Transcription -- Estrogen Signaling Mechanisms -- Signal Transduction Pathways Involved in Glucocorticoid Actions -- Reactive Signaling Molecules -- Cellular Signaling by Reactive Oxygen Species: Biochemical Basis and Physiological Scope -- Soluble Guanylyl Cyclase: The Nitric Oxide Receptor -- Cell Cycle, Cell Death and Cancer -- Distinct Roles of the Pocket Proteins in the Control of Cell Cycle -- Activation of the p53 Tumor Suppressor and its Multiple Roles in Cell Cycle and Apoptosis -- Aging and Cancer: Caretakers and Gatekeepers -- Signal Transduction in Embryonic Stem Cells and the Rise of iPS Cells -- Erratum to. |
| 520 ## - NOTA DE RESUMEN, ETC. |
|---|
| Summary, etc. |
This book was adapted from graduate courses on signal transduction taught by the editor, where the need for a good overview of recent developments on each of the topics being discussed became apparent. Given the wide range of research topics in signaling, a selection was made that not only reflects the current research interest, but also anticipates those areas that will continue to be of interest over the next several years. The health-relatedness of research was a major criterion for selection, as can be seen in the list of topics covered, such as G protein coupled receptors, growth factors, nuclear receptors, reactive oxygen and nitrogen species, the cell cycle and cancer. The emphasis is on areas of signaling research with direct clinical significance. Another field covered, one rarely highlighted in signal transduction books, is that of signaling platforms, which has been emerging as a significant research area relevant to cellular metabolism, cell proliferation, differentiation, apoptosis, neurodegenerative diseases, and cancer. |
| 596 ## - |
|---|
| -- |
19 |
| 650 #0 - ASIENTO SECUNDARIO DE MATERIA - TERMINO TEMÁTICO |
|---|
| Topical term or geographic name as entry element |
Life sciences. |
| 650 #0 - ASIENTO SECUNDARIO DE MATERIA - TERMINO TEMÁTICO |
|---|
| Topical term or geographic name as entry element |
Medicine. |
| 650 #0 - ASIENTO SECUNDARIO DE MATERIA - TERMINO TEMÁTICO |
|---|
| Topical term or geographic name as entry element |
RNA-ligand interactions. |
| 650 #0 - ASIENTO SECUNDARIO DE MATERIA - TERMINO TEMÁTICO |
|---|
| Topical term or geographic name as entry element |
Cell receptors. |
| 650 #0 - ASIENTO SECUNDARIO DE MATERIA - TERMINO TEMÁTICO |
|---|
| Topical term or geographic name as entry element |
Cytology. |
| 650 14 - ASIENTO SECUNDARIO DE MATERIA - TERMINO TEMÁTICO |
|---|
| Topical term or geographic name as entry element |
Life Sciences. |
| 650 24 - ASIENTO SECUNDARIO DE MATERIA - TERMINO TEMÁTICO |
|---|
| Topical term or geographic name as entry element |
Cell Biology. |
| 650 24 - ASIENTO SECUNDARIO DE MATERIA - TERMINO TEMÁTICO |
|---|
| Topical term or geographic name as entry element |
Molecular Medicine. |
| 650 24 - ASIENTO SECUNDARIO DE MATERIA - TERMINO TEMÁTICO |
|---|
| Topical term or geographic name as entry element |
Protein-Ligand Interactions. |
| 650 24 - ASIENTO SECUNDARIO DE MATERIA - TERMINO TEMÁTICO |
|---|
| Topical term or geographic name as entry element |
Receptors. |
| 710 2# - ASIENTO SECUNDARIO - NOMBRE CORPORATIVO |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Relationship information |
Printed edition: |
| International Standard Book Number |
9783642021114 |
| 856 40 - LOCALIZACIÓN Y ACCESO ELECTRÓNICOS |
|---|
| Public note |
Libro electrónico |
| Uniform Resource Identifier |
<a href="http://148.231.10.114:2048/login?url=http://link.springer.com/book/10.1007/978-3-642-02112-1">http://148.231.10.114:2048/login?url=http://link.springer.com/book/10.1007/978-3-642-02112-1</a> |
| 942 ## - TIPO DE MATERIAL (KOHA) |
|---|
| Koha item type |
Libro Electrónico |
