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03406cam a2200445Mi 4500 |
| 001 - NÚMERO DE CONTROL |
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u380068 |
| 003 - IDENTIFICADOR DEL NÚMERO DE CONTROL |
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SIRSI |
| 005 - FECHA Y HORA DE LA ULTIMA TRANSACCIÓN |
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20160812084628.0 |
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140222s2014 vtu o 000 0 eng d |
| 040 ## - FUENTE DE CATALOGACIÓN |
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| Original cataloging agency |
EBLCP |
| Language of cataloging |
eng |
| Description conventions |
pn |
| Transcribing agency |
EBLCP |
| Modifying agency |
OCLCQ |
| -- |
OPELS |
| -- |
NT |
| -- |
YDXCP |
| -- |
UIU |
| -- |
OCLCQ |
| -- |
OCLCO |
| -- |
OCLCQ |
| 020 ## - NÚMERO INTERNACIONAL NORMALIZADO PARA LIBROS |
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| International Standard Book Number |
9780128004982 |
| Qualifying information |
(electronic bk.) |
| 020 ## - NÚMERO INTERNACIONAL NORMALIZADO PARA LIBROS |
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| International Standard Book Number |
0128004983 |
| Qualifying information |
(electronic bk.) |
| 029 1# - OTHER SYSTEM CONTROL NUMBER (OCLC) |
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| OCLC library identifier |
DEBSZ |
| System control number |
414272064 |
| 029 1# - OTHER SYSTEM CONTROL NUMBER (OCLC) |
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| OCLC library identifier |
NLGGC |
| System control number |
37319269X |
| 050 #4 - SIGNATURA TOPOGRÁFICA DE LA BIBLIOTECA DEL CONGRESO |
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| Classification number |
RD261 |
| 082 04 - NÚMERO DE CLASIFICACIÓN DECIMAL DEWEY |
|---|
| Classification number |
617.092 |
| 049 ## - LOCAL HOLDINGS (OCLC) |
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| Holding library |
TEFA |
| 100 1# - ASIENTO PRINCIPAL--NOMBRE PERSONAL |
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| Personal name |
Kozlov, Andrei P. |
| 245 10 - MENCIÓN DE TITULO |
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| Title |
Evolution by tumor neofunctionalization |
| Medium |
[recurso electrónico] : |
| Remainder of title |
the role of tumors in the origin of new cell types, tissues and organs / |
| Statement of responsibility, etc. |
by Andrei P. Kozlov. |
| 260 ## - PUBLICACIÓN, DISTRIBUCIÓN, ETC. (PIE DE IMPRENTA) |
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| Place of publication, distribution, etc. |
Burlington : |
| Name of publisher, distributor, etc. |
Elsevier Science, |
| Date of publication, distribution, etc. |
2014. |
| 300 ## - DESCRIPCIÓN FÍSICA |
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| Extent |
1 online resource (248 pages) |
| 336 ## - CONTENT TYPE |
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| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
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| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
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| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 505 0# - NOTA DE CONTENIDO |
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| Formatted contents note |
1. The modern synthesis of evolutionary biology and the health sciences -- 2. Evolution and pathology -- 3. The widespread occurrences of tumors in multicellular organisms -- 4. Features of tumors that could be used in evolution -- 5. Tumors might participate in the evolution of ontogenesis -- 6. Tumors that might play a role in evolution -- 7. Tumors that have played a role in evolution -- 8. The general principles and molecular mechanism in the orgin of novel genes -- 9. The origin of evolutionary novel genes and the evolution of new functions and structural complexity of multicellular organisms -- 10. The orgin of new cell types, tissues and organs by tumor neofunctionalization -- 11. Experimental confirmation of nontrivial predictions of evolution by the tumor neofunctionalization hypothesis -- 12. Other evidence supporting the positive evolutionary role of tumors and the hypothesis of evolution by tumor neofunctionalization. |
| 520 ## - NOTA DE RESUMEN, ETC. |
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| Summary, etc. |
Evolution by Tumor Neofunctionalization explores the possibility of the positive role of tumors in evolution of multicellular organisms. This unique perspective goes beyond recent publications on how evolution may influence tumors, to consider the possible role of tumors in evolution. Widespread in nature tumors represent a much broader category than malignant tumors only. The majority of tumors in humans and other animals may never undergo malignant transformation. Tumors may differentiate with the loss of malignancy, and malignant tumors may spontaneously regress. Cellular oncogenes and tumor suppressor genes play roles in normal development. Many features of tumors could be used in evolution, and there are examples of tumors that have played a role in evolution. |
| 588 0# - SOURCE OF DESCRIPTION NOTE |
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| Source of description note |
Print version record. |
| 596 ## - |
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| -- |
19 |
| 650 #0 - ASIENTO SECUNDARIO DE MATERIA - TERMINO TEMÁTICO |
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| Topical term or geographic name as entry element |
Tumors |
| General subdivision |
Molecular aspects. |
| 650 #0 - ASIENTO SECUNDARIO DE MATERIA - TERMINO TEMÁTICO |
|---|
| Topical term or geographic name as entry element |
Evolution (Biology) |
| 650 #4 - ASIENTO SECUNDARIO DE MATERIA - TERMINO TEMÁTICO |
|---|
| Topical term or geographic name as entry element |
Tumors. |
| 650 #7 - ASIENTO SECUNDARIO DE MATERIA - TERMINO TEMÁTICO |
|---|
| Topical term or geographic name as entry element |
MEDICAL |
| General subdivision |
Surgery |
| -- |
General. |
| Source of heading or term |
bisacsh |
| 655 #4 - |
|---|
| -- |
Electronic books. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
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| Relationship information |
Print version: |
| Main entry heading |
Kozlov, Andrei P. |
| Title |
Evolution by Tumor Neofunctionalization : The Role of Tumors in the Origin of New Cell Types, Tissues and Organs. |
| Place, publisher, and date of publication |
Burlington : Elsevier Science, 2014 |
| International Standard Book Number |
9780128001653 |
| 856 40 - LOCALIZACIÓN Y ACCESO ELECTRÓNICOS |
|---|
| Public note |
Libro electrónico |
| Materials specified |
ScienceDirect |
| Uniform Resource Identifier |
<a href="http://148.231.10.114:2048/login?url=http://www.sciencedirect.com/science/book/9780128001653">http://148.231.10.114:2048/login?url=http://www.sciencedirect.com/science/book/9780128001653</a> |
| 942 ## - TIPO DE MATERIAL (KOHA) |
|---|
| Koha item type |
Libro Electrónico |
