Quasispecies: From Theory to Experimental Systems (Registro nro. 225634)

MARC details
000 -LIDER
fixed length control field 03654nam a22005175i 4500
001 - CONTROL NUMBER
control field 978-3-319-23898-2
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20180206182942.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 160318s2016 gw | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9783319238982
-- 978-3-319-23898-2
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number QR355-502
072 #7 - SUBJECT CATEGORY CODE
Subject category code MMFM
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED052000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 616.9101
Edition number 23
245 10 - TITLE STATEMENT
Title Quasispecies: From Theory to Experimental Systems
Medium [recurso electrónico] /
Statement of responsibility, etc. edited by Esteban Domingo, Peter Schuster.
250 ## - EDITION STATEMENT
Edition statement 1st ed. 2016.
264 #1 -
-- Cham :
-- Springer International Publishing :
-- Imprint: Springer,
-- 2016.
300 ## - PHYSICAL DESCRIPTION
Extent XIV, 357 p. 67 illus., 53 illus. in color.
Other physical details online resource.
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-- computer
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-- rdamedia
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-- online resource
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347 ## -
-- text file
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490 1# - SERIES STATEMENT
Series statement Current Topics in Microbiology and Immunology,
International Standard Serial Number 0070-217X ;
Volume/sequential designation 392
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note What is a quasispecies?- Historical origins and current scope -- The nucleation of semantic information in prebiotic matter -- Evolution of RNA-based networks -- Quasispecies on fitness landscapes -- Mathematical models of quasispecies theory and exact results for the dynamics -- Theoretical Models of Generalized Quasispecies -- Theories of lethal mutagenesis: from error catastrophe to lethal defection -- Estimating fitness of viral quasispecies from next-generation sequencing data -- Getting to know viral evolutionary strategies: Towards the next generation of quasispecies models -- Cooperative Interaction within RNA Virus Mutant Spectra -- Arenavirus Quasispecies And Their Biological Implications -- Models of viral population dynamics -- Fidelity variants and RNA quasispecies -- Antiviral strategies based on lethal mutagenesis and error threshold.
520 ## - SUMMARY, ETC.
Summary, etc. This volume brings together recent developments in quasispecies theory extended to variable environments and practical applications in elucidating viral dynamics and treatment designs. In particular, the existence of an error threshold in rugged fitness landscapes has opened the way to a new antiviral strategy termed lethal mutagenesis, which is now under intensive theoretical, experimental and clinical investigation. As such the book explains how an understanding of quasispecies dynamics within infected organisms has increased our knowledge of viral disease events. From a clinical perspective, population dynamics highlights important problems for viral disease control, such as the selection of drug-resistant mutants that often accompanies treatment failures, and suggests means of increasing the effectiveness of antiviral treatments. The book is intended for students and scientists interested in basic and applied aspects of biophysics, chemistry, biology, evolution and medical virology..
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Medicine.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Human genetics.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Immunology.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Virology.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Biomedicine.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Virology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Human Genetics.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Immunology.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Domingo, Esteban.
Relator term editor.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Schuster, Peter.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Printed edition:
International Standard Book Number 9783319238975
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Current Topics in Microbiology and Immunology,
-- 0070-217X ;
Volume number/sequential designation 392
856 40 - ELECTRONIC LOCATION AND ACCESS
Public note Libro electrónico
Uniform Resource Identifier http://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-3-319-23898-2
912 ## -
-- ZDB-2-SBL
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Libro Electrónico
Existencias
Estado de retiro Colección Ubicación permanente Ubicación actual Fecha de ingreso Total Checkouts Date last seen Número de copia Tipo de material
  Colección de Libros Electrónicos Biblioteca Electrónica Biblioteca Electrónica 06/02/2018   06/02/2018 1 Libro Electrónico

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