Organic Cation Transporters (Registro nro. 226219)

MARC details
000 -LIDER
fixed length control field 03853nam a22005055i 4500
001 - CONTROL NUMBER
control field 978-3-319-23793-0
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20180206183012.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 151217s2016 gw | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9783319237930
-- 978-3-319-23793-0
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number QP34-38
072 #7 - SUBJECT CATEGORY CODE
Subject category code MFG
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED075000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 612
Edition number 23
245 10 - TITLE STATEMENT
Title Organic Cation Transporters
Medium [recurso electrónico] :
Remainder of title Integration of Physiology, Pathology, and Pharmacology /
Statement of responsibility, etc. edited by Giuliano Ciarimboli, Sophie Gautron, Eberhard Schlatter.
250 ## - EDITION STATEMENT
Edition statement 1st ed. 2016.
264 #1 -
-- Cham :
-- Springer International Publishing :
-- Imprint: Springer,
-- 2016.
300 ## - PHYSICAL DESCRIPTION
Extent XV, 264 p. 34 illus., 14 illus. in color.
Other physical details online resource.
336 ## -
-- text
-- txt
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-- computer
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-- rdamedia
338 ## -
-- online resource
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347 ## -
-- text file
-- PDF
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505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Introduction to the cellular transport of organic cations -- Functional properties of organic cation transporter OCT1, binding of substrates and inhibitors, and presumed transport mechanism -- Pharmacological and toxicological significance of the organic cation transporters OCT and MATE: Drug disposition, interaction and toxicity -- Genetic variability in organic cation transporters: pathophysiological manifestations and consequences for drug pharmacokinetics and efficacy -- Physiological and pathological regulation of transporters for organic cations -- Endocrine and metabolic regulation of transporters for organic cations -- Organic cation transporters (OCTs) as modulators of behavior and mood -- Organic cation transporters as modulators of neurodegeneration and neuroprotection -- Translational relevance of animal models for the study of organic cation transporter function -- Role of transporters for organic cations in plants for environmental cycling of pharmaceutical residues.
520 ## - SUMMARY, ETC.
Summary, etc. This innovative text explores the cellular transport of organic cations, from functional and structural properties to pharmacological implications and psychiatric developments. The authoritative chapters introduce organic cation transporters and then proceed to discuss their mechanisms such as binding of substrates and inhibitors; their drug dispositions and toxicity; their relationships to genetic and pathophysiological variability; and their roles in endocrine, metabolic, and neurological systems. The final chapters delve into the use of animal models for the study of organic cation transporter function and their possible use in environmental cycling of pharmaceutical residues. This comprehensive volume unites integrative transporter physiology with structural and molecular biology, genetics, pharmacology and pathophysiology, offering a holistic approach to utilizing this novel technique in physiological contexts. It will prove invaluable reading for researchers and students in various areas of integrative, organ, cell and molecular physiology as well as pharmacologists and neurologists.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Medicine.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Human physiology.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Pharmacology.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Pathology.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Biomedicine.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Human Physiology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Pharmacology/Toxicology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Pathology.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Ciarimboli, Giuliano.
Relator term editor.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Gautron, Sophie.
Relator term editor.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Schlatter, Eberhard.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Printed edition:
International Standard Book Number 9783319237923
856 40 - ELECTRONIC LOCATION AND ACCESS
Public note Libro electrónico
Uniform Resource Identifier http://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-3-319-23793-0
912 ## -
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942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Libro Electrónico
Existencias
Estado de retiro Colección Ubicación permanente Ubicación actual Fecha de ingreso Total Checkouts Date last seen Número de copia Tipo de material
  Colección de Libros Electrónicos Biblioteca Electrónica Biblioteca Electrónica 06/02/2018   06/02/2018 1 Libro Electrónico

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