MARC details
000 -LIDER |
fixed length control field |
04053nam a22004815i 4500 |
001 - CONTROL NUMBER |
control field |
978-3-319-42023-3 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
DE-He213 |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20180206183018.0 |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
fixed length control field |
cr nn 008mamaa |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
161013s2016 gw | s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9783319420233 |
-- |
978-3-319-42023-3 |
050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
RC261-271 |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
MJCL |
Source |
bicssc |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
MED062000 |
Source |
bisacsh |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
Classification number |
614.5999 |
Edition number |
23 |
245 10 - TITLE STATEMENT |
Title |
Systems Biology of Tumor Microenvironment |
Medium |
[recurso electrónico] : |
Remainder of title |
Quantitative Modeling and Simulations / |
Statement of responsibility, etc. |
edited by Katarzyna A. Rejniak. |
264 #1 - |
-- |
Cham : |
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Springer International Publishing : |
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Imprint: Springer, |
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2016. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
XVII, 249 p. 93 illus., 80 illus. in color. |
Other physical details |
online resource. |
336 ## - |
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text |
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txt |
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rdacontent |
337 ## - |
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computer |
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c |
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rdamedia |
338 ## - |
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online resource |
-- |
cr |
-- |
rdacarrier |
347 ## - |
-- |
text file |
-- |
PDF |
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rda |
490 1# - SERIES STATEMENT |
Series statement |
Advances in Experimental Medicine and Biology, |
International Standard Serial Number |
0065-2598 ; |
Volume/sequential designation |
936 |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
Foreword -- Preface -- List of Contributors -- Image Analysis of the Tumor Microenvironment -- Hypoxia in Gliomas: Opening Therapeutical Opportunities Using a Mathematical-Based Approach -- Computer Simulations of the Tumor Vasculature: Applications to Interstitial Fluid Flow, Drug Delivery, and Oxygen -- Cell-ECM Interactions in Tumor Invasion -- Circulating Tumor Cells: When Solid tumor Meets Fluid Microenvironment -- Modeling Proteolytically Driven Tumor Lymphangiogenesis -- Positive feedback loops between inflammatory, bone and cancer cells during metastatic niche construction -- Microenvironmental Niches and Sanctuaries: a Route to Acquired Resistance -- The Tumor Microenvironment as a Barrier to Cancer Nanotherapy -- Microenvironment-Mediated Modeling of Tumor Response to Vascular-Targeting Drugs -- Optimizing Chemotherapeutic Anti-Cancer Treatment and the Tumor Microenvironment: An Analysis of Mathematical Models -- Progress towards computational 3-D multicellular systems biology -- Index. |
520 ## - SUMMARY, ETC. |
Summary, etc. |
This edited volume discusses the complexity of tumor microenvironments during cancer development, progression and treatment. Each chapter presents a different mathematical model designed to investigate the interactions between tumor cells and the surrounding stroma and stromal cells. The topics covered in this book include the quantitative image analysis of a tumor microenvironment, the microenvironmental barriers in oxygen and drug delivery to tumors, the development of tumor microenvironmental niches and sanctuaries, intravenous transport of the circulating tumor cells, the role of the tumor microenvironment in chemotherapeutic interventions, the interactions between tumor cells, the extracellular matrix, the interstitial fluid, and the immune and stromal cells. Mathematical models discussed here embrace both continuous and agent-based approaches, as well as mathematical frameworks of solid mechanics, fluid dynamics and optimal control theory. The topics in each chapter will be of interest to a biological community wishing to apply the mathematical methods to interpret their experimental data, and to a biomathematical audience interested in exploring how mathematical models can be used to address complex questions in cancer biology. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Término temático o nombre geográfico como elemento de entrada |
Medicine. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Término temático o nombre geográfico como elemento de entrada |
Cancer research. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Término temático o nombre geográfico como elemento de entrada |
Biomathematics. |
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Término temático o nombre geográfico como elemento de entrada |
Biomedicine. |
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Término temático o nombre geográfico como elemento de entrada |
Cancer Research. |
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Término temático o nombre geográfico como elemento de entrada |
Mathematical and Computational Biology. |
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Término temático o nombre geográfico como elemento de entrada |
Biological and Medical Physics, Biophysics. |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Rejniak, Katarzyna A. |
Relator term |
editor. |
710 2# - ADDED ENTRY--CORPORATE NAME |
Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
773 0# - HOST ITEM ENTRY |
Title |
Springer eBooks |
776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
Relationship information |
Printed edition: |
International Standard Book Number |
9783319420219 |
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
Uniform title |
Advances in Experimental Medicine and Biology, |
-- |
0065-2598 ; |
Volume number/sequential designation |
936 |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Public note |
Libro electrónico |
Uniform Resource Identifier |
http://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-3-319-42023-3 |
912 ## - |
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ZDB-2-SBL |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Libro Electrónico |