Sirtuins (Registro nro. 227769)

MARC details
000 -LIDER
fixed length control field 03819nam a22005175i 4500
001 - CONTROL NUMBER
control field 978-94-024-0962-8
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20180206183132.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 161117s2016 ne | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9789402409628
-- 978-94-024-0962-8
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RC261-271
072 #7 - SUBJECT CATEGORY CODE
Subject category code MJCL
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED062000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 614.5999
Edition number 23
245 10 - TITLE STATEMENT
Title Sirtuins
Medium [recurso electrónico] /
Statement of responsibility, etc. edited by Riekelt H. Houtkooper.
264 #1 -
-- Dordrecht :
-- Springer Netherlands :
-- Imprint: Springer,
-- 2016.
300 ## - PHYSICAL DESCRIPTION
Extent VIII, 288 p. 30 illus., 24 illus. in color.
Other physical details online resource.
336 ## -
-- text
-- txt
-- rdacontent
337 ## -
-- computer
-- c
-- rdamedia
338 ## -
-- online resource
-- cr
-- rdacarrier
347 ## -
-- text file
-- PDF
-- rda
490 1# - SERIES STATEMENT
Series statement Proteins and Cell Regulation ;
Volume/sequential designation 10
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note General introduction, Riekelt H. Houtkooper -- Biochemistry and Enzymology of Sirtuins, Yue Yang and Anthony A. Sauve -- NAD+ as a pharmacological tool to boost sirtuin activity, Riekelt H. Houtkooper -- Protein lysine acylation: abundance, dynamics and function, Olga Pougovkina and Vincent C. J. de Boer -- SIRT1 in metabolic health and disease, Marie Boutant and Carles Cantó -- Deacetylation by SIRT3 relieves inhibition of mitochondrial protein function, Peter Chhoy, Kristin A. Anderson, Kathleen A. Hershberger, Frank K. Huynh, Angelical S. Martin, Eoin McDonnell, Brett S. Peterson, Laura A. Starzenski, Donald S. Backos, Kristofer S. Fritz, and Matthew D. Hirschey -- SIRT5 reveals novel enzymatic activities of sirtuins, Bin He and Hening Lin -- Diverse roles for SIRT6 in mammalian healthspan and longevity, Bernadette M. M. Zwaans, William Giblin and David B. Lombard -- Sirtuins in cancer ? emerging role as modulators of metabolic reprogramming, Jaewon J. Lee, Karina N. Gonzalez Herrera and Marcia C. Haigis -- Sirtuins as metabolic modulators of muscle plasticity, Keir Menzies, Julien Francisco Zaldivar-Jolissaint and Johan Auwerx -- Sirtuins and aging, Carles Cantó and Riekelt Houtkooper -- Sirtuins and the Circadian Clock: Epigenetic and Metabolic Crosstalk, Selma Masri, Marina Maria Bellet and Paolo Sassone-Corsi -- Sirtuin activation by small molecules, Hassina Massudi, Lindsay E. Wu, and David A. Sinclair -- Future perspective, Brian Kennedy -- Index.
520 ## - SUMMARY, ETC.
Summary, etc. The sirtuin family of proteins (SIRT1-7) received a lot of attention in recent years as they serve as metabolic sensors that control not only metabolism, but also aging and lifespan regulation. As such, sirtuins are strong targets for the treatment of age-related metabolic diseases, including obesity, diabetes, and cancer. Indeed, many research groups as well as pharmaceutical companies discovered food components and/or drugs that target the sirtuins and provide significant health benefits. This book focuses on various aspects of sirtuin biology, from basic biochemistry, via molecular function, to its role in (fighting) human disease.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Medicine.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Cancer research.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Molecular biology.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Diabetes.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Metabolic diseases.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Biomedicine.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Cancer Research.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Metabolic Diseases.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Diabetes.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Molecular Medicine.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Houtkooper, Riekelt H.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Printed edition:
International Standard Book Number 9789402409611
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Proteins and Cell Regulation ;
Volume number/sequential designation 10
856 40 - ELECTRONIC LOCATION AND ACCESS
Public note Libro electrónico
Uniform Resource Identifier http://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-94-024-0962-8
912 ## -
-- ZDB-2-SBL
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Libro Electrónico
Existencias
Estado de retiro Colección Ubicación permanente Ubicación actual Fecha de ingreso Total Checkouts Date last seen Número de copia Tipo de material
  Colección de Libros Electrónicos Biblioteca Electrónica Biblioteca Electrónica 06/02/2018   06/02/2018 1 Libro Electrónico

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