MARC details
| 000 -LIDER |
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| fixed length control field |
03351nam a22004935i 4500 |
| 001 - CONTROL NUMBER |
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| control field |
978-3-319-42223-7 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20180206183142.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
160830s2016 gw | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9783319422237 |
| -- |
978-3-319-42223-7 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
RC261-271 |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MJCL |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MED062000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
614.5999 |
| Edition number |
23 |
| 245 10 - TITLE STATEMENT |
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| Title |
Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy |
| Medium |
[recurso electrónico] / |
| Statement of responsibility, etc. |
edited by Emmanuel Donnadieu. |
| 264 #1 - |
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| -- |
Cham : |
| -- |
Springer International Publishing : |
| -- |
Imprint: Springer, |
| -- |
2016. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
VIII, 199 p. 27 illus., 19 illus. in color. |
| Other physical details |
online resource. |
| 336 ## - |
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| -- |
text |
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txt |
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rdacontent |
| 337 ## - |
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computer |
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c |
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rdamedia |
| 338 ## - |
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| -- |
online resource |
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cr |
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rdacarrier |
| 347 ## - |
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| -- |
text file |
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PDF |
| -- |
rda |
| 490 1# - SERIES STATEMENT |
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| Series statement |
Resistance to Targeted Anti-Cancer Therapeutics, |
| International Standard Serial Number |
2196-5501 ; |
| Volume/sequential designation |
9 |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Introduction -- Basic rules of T cell migration -- Regulation of anti-tumor T cell migration and function: contribution of real-time imaging -- Vascular normalization, T cell trafficking and anti-tumor immunity -- Disruption of anti-tumor T cell responses by cancer-associated fibroblasts -- Cancer-associated Tertiary Lymphoid Structures, from basic knowledge toward therapeutic target in clinic -- Homing Improvement: Boosting T Cell Trafficking for Cancer Immunotherapy -- Chemokines and T cell trafficking into tumors. Strategies to enhance recruitment of T cells into tumors -- Strategies to enhance migration and persistence of chimeric antigen receptor (CAR)-T cells into tumors. |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy. The volume includes three sections. The first section covers general knowledge about T cell trafficking during a normal immune response but also during tumor development. The second section provides an in-depth description of the different obstacles that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Término temático o nombre geográfico como elemento de entrada |
Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Término temático o nombre geográfico como elemento de entrada |
Cancer research. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Término temático o nombre geográfico como elemento de entrada |
Immunology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Término temático o nombre geográfico como elemento de entrada |
Molecular biology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Término temático o nombre geográfico como elemento de entrada |
Biomedicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Término temático o nombre geográfico como elemento de entrada |
Cancer Research. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Término temático o nombre geográfico como elemento de entrada |
Immunology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Término temático o nombre geográfico como elemento de entrada |
Molecular Medicine. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Donnadieu, Emmanuel. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
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| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
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| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
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| Relationship information |
Printed edition: |
| International Standard Book Number |
9783319422213 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
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| Uniform title |
Resistance to Targeted Anti-Cancer Therapeutics, |
| -- |
2196-5501 ; |
| Volume number/sequential designation |
9 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Public note |
Libro electrónico |
| Uniform Resource Identifier |
http://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-3-319-42223-7 |
| 912 ## - |
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ZDB-2-SBL |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Libro Electrónico |
