MARC details
| 000 -LIDER |
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| fixed length control field |
04675nam a22006255i 4500 |
| 001 - CONTROL NUMBER |
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| control field |
978-3-319-74186-4 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20210201191400.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
180823s2018 gw | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9783319741864 |
| -- |
978-3-319-74186-4 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
QR177 |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MMG |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
MED071000 |
| Source |
bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
MKG |
| Source |
thema |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
616.9041 |
| Edition number |
23 |
| 245 10 - TITLE STATEMENT |
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| Title |
Drug Resistance in Leishmania Parasites |
| Medium |
[electronic resource] : |
| Remainder of title |
Consequences, Molecular Mechanisms and Possible Treatments / |
| Statement of responsibility, etc. |
edited by Alicia Ponte-Sucre, Maritza Padrón-Nieves. |
| 250 ## - EDITION STATEMENT |
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| Edition statement |
2nd ed. 2018. |
| 264 #1 - |
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| -- |
Cham : |
| -- |
Springer International Publishing : |
| -- |
Imprint: Springer, |
| -- |
2018. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
XVII, 376 p. 24 illus., 14 illus. in color. |
| Other physical details |
online resource. |
| 336 ## - |
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| -- |
text |
| -- |
txt |
| -- |
rdacontent |
| 337 ## - |
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| -- |
computer |
| -- |
c |
| -- |
rdamedia |
| 338 ## - |
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| -- |
online resource |
| -- |
cr |
| -- |
rdacarrier |
| 347 ## - |
|---|
| -- |
text file |
| -- |
PDF |
| -- |
rda |
| 500 ## - GENERAL NOTE |
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| General note |
Acceso multiusuario |
| 505 0# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
Prologue -- Introduction -- Part I Determinant features in Leishmaniasis -- Molecular evolution and phylogeny of Leishmania -- The role of reservoirs: canine Leishmaniasis -- Epidemiology of Leishmaniasis in the time of drug resistance -- The role of the immune system in resistance to infection -- Part II Challenges in the diagnosis, treatment and control of Leishmaniasis in the times of drug resistance -- Co-infection with HIV -- Visceral Leishmaniasis -- Tegumentary Leishmaniasis -- Antimony accounted sequel post Kala-Azar dermal Leishmaniasis -- Part III Molecular featrues of drug resistant Leishmania -- Genetic Expression and drug resistance, the role of proteomics -- The role of AMC transporters in drug-resistant Leishmania -- Functional analysis of Leishmania membrane (non AMC) transporters involved in drug resistance -- Part IV Pharmacology and chemotherapy of Leishmaniasis -- Classical vs. novel treatment regimens -- Bioinformatics in Leishmania drug design -- Leishmanis mitochondria, a druggable organelle -- P-glycoprotein-like transporters in Leishmania: a search for reversal agents -- Part V Strategies to circumvent drug resistance in Leishmania -- The relevance of susceptibility tests, breakpoints and markers -- The concept of fitness in Leishmania. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Drug resistance is a fundamental factor in treatment failure in diseases like leishmaniasis, although additional factors also play a role in this phenomenon. This volume is the second edition of a well-received book that provides a comprehensive update on the pathology of the disease, as well as on the concept of parasitic drug resistance, its molecular basis, consequences and possible treatments. A valuable resource for scientists both from academia and industry involved in biomedical research and drug design, the book provides the knowledge needed to understand leishmaniasis and to contibute to combatting this disease worldwide. |
| 541 ## - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Owner |
UABC ; |
| Method of acquisition |
Temporal ; |
| Date of acquisition |
01/01/2021-12/31/2023. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Término temático o nombre geográfico como elemento de entrada |
Drug resistance. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Término temático o nombre geográfico como elemento de entrada |
Infectious diseases. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Término temático o nombre geográfico como elemento de entrada |
Pharmaceutical technology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Término temático o nombre geográfico como elemento de entrada |
Vaccines. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Término temático o nombre geográfico como elemento de entrada |
Parasitology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Término temático o nombre geográfico como elemento de entrada |
Microbiology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Término temático o nombre geográfico como elemento de entrada |
Drug Resistance. |
| -- |
https://scigraph.springernature.com/ontologies/product-market-codes/B16020 |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Término temático o nombre geográfico como elemento de entrada |
Infectious Diseases. |
| -- |
https://scigraph.springernature.com/ontologies/product-market-codes/H33096 |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Término temático o nombre geográfico como elemento de entrada |
Pharmaceutical Sciences/Technology. |
| -- |
https://scigraph.springernature.com/ontologies/product-market-codes/B21010 |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Término temático o nombre geográfico como elemento de entrada |
Vaccine. |
| -- |
https://scigraph.springernature.com/ontologies/product-market-codes/B16010 |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Término temático o nombre geográfico como elemento de entrada |
Parasitology. |
| -- |
https://scigraph.springernature.com/ontologies/product-market-codes/B19002 |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Término temático o nombre geográfico como elemento de entrada |
Microbiology. |
| -- |
https://scigraph.springernature.com/ontologies/product-market-codes/L23004 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Ponte-Sucre, Alicia. |
| Relator term |
editor. |
| Relator code |
edt |
| -- |
http://id.loc.gov/vocabulary/relators/edt |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Padrón-Nieves, Maritza. |
| Relator term |
editor. |
| Relator code |
edt |
| -- |
http://id.loc.gov/vocabulary/relators/edt |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer Nature eBook |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Relationship information |
Printed edition: |
| International Standard Book Number |
9783319741857 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Relationship information |
Printed edition: |
| International Standard Book Number |
9783319741871 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Relationship information |
Printed edition: |
| International Standard Book Number |
9783030089306 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Public note |
Libro electrónico |
| Uniform Resource Identifier |
http://148.231.10.114:2048/login?url=https://doi.org/10.1007/978-3-319-74186-4 |
| 912 ## - |
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| -- |
ZDB-2-SBL |
| 912 ## - |
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| -- |
ZDB-2-SXB |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Koha item type |
Libro Electrónico |
