Mitochondrial Biology and Experimental Therapeutics (Registro nro. 243756)

MARC details
000 -LIDER
fixed length control field 05705nam a22005655i 4500
001 - CONTROL NUMBER
control field 978-3-319-73344-9
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20210201191448.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 180321s2018 gw | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9783319733449
-- 978-3-319-73344-9
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RM1-950
072 #7 - SUBJECT CATEGORY CODE
Subject category code MMG
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED071000
Source bisacsh
072 #7 - SUBJECT CATEGORY CODE
Subject category code MKG
Source thema
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 615
Edition number 23
245 10 - TITLE STATEMENT
Title Mitochondrial Biology and Experimental Therapeutics
Medium [electronic resource] /
Statement of responsibility, etc. edited by Paulo J. Oliveira.
250 ## - EDITION STATEMENT
Edition statement 1st ed. 2018.
264 #1 -
-- Cham :
-- Springer International Publishing :
-- Imprint: Springer,
-- 2018.
300 ## - PHYSICAL DESCRIPTION
Extent IX, 708 p. 127 illus., 106 illus. in color.
Other physical details online resource.
336 ## -
-- text
-- txt
-- rdacontent
337 ## -
-- computer
-- c
-- rdamedia
338 ## -
-- online resource
-- cr
-- rdacarrier
347 ## -
-- text file
-- PDF
-- rda
500 ## - GENERAL NOTE
General note Acceso multiusuario
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Target Mitochondria -- SECTION I-Mitochondrial Biology -- Introduction: Mitochondria: the cell furnace -- MItochondria: Where are They Coming From? -- Mitochondrial Dynamics: A journey from Mitochondrial Morphology to MItochondrial Function and Quality -- Mitochondrial ROS, Oxidative Stress.and Aging- The Mitochondrial Permeability Transition Pore -- Mitochondrial Regulation of Cell Death -- MItochondria in Liver Diseases -- Mitochondria in Liver Regeneration,Energy Metabolism, and Posthepatectomy Liver Dysfunction -- MItochondrial Remodeling in Cancer -- Mitochondria in Kidney Disease -- CNS diseases and disruption of Mitochondria -- Mitochondrial disruption in cardiovascular diseases -- .Drug-inducing Mitochondrial Toxicity -- MItochondrial DNA: Functions and Role in Acquired Diseases -- SECTION II-MItochondrial Therapeutics: From the Bench to Industry and Patient -- The Evolution of Mitochondrial Toxicity Assessment in Industry -- Designing Mitochondrial-Active Molecules: The Road to MitoQ and Beyond -- Recovering Mitochondrial Function in Patients' Fibroblasts -- Targeting Mitochondria with Sweat: Improving Mitochondrial Function with Physical Activity -- Modulation of Cell Fate by Tauroursodexycholic Acid: All Paths Lead to Mitochondria -- Pharmacological Targeting of the Mitchondrial Permeability Transition Pore -- Strategies to Preserve/Improve Mitochondrial Function in Organ Preservation Solutions -- MItochondrial Targeted Redox Active Compounds and the Astrocytemotoneuron Axis: relevance for the Treatment of Amyotrophic Lateral Sclerosis -- Targeting the Mitochondrial Genome Through a Nanocarrier and the Regulation of the Mitochondrial Gene Experssion -- Mitochoncrial Dysfunction and Chronic Disease: Treatment with Membrane Lipid Replacement and other Natural Supplements -- Development of Mitochondrial-Directed Plastoquinones -- Targeted Mitochondrial Genome Editing -- Targeting Therpeutic Nucleic Acids into Mitochondria: A Long Challenge -- Cell Permeable Peptides Targeting Mitochondria -- MItochondrial -Directed Cancer Therapy -- SkQ1: The Road from the Bench to the Market -- MItochondrial Follies: Comic.
520 ## - SUMMARY, ETC.
Summary, etc. This book addresses the therapeutic strategies to target mitochondrial metabolism in diseases where the function of that organelle is compromised, and it discusses the effective strategies used to create mitochondrial-targeted agents that can become commercially available drug delivery platforms. The consistent growth of research focused in understanding the multifaceted role of mitochondria in cellular metabolism, controlling pathways related with cell death, and ionic/redox regulation has extended the research of mitochondrial chemical-biological interactions to include various pharmacological and toxicological applications. Not only does the book extensively cover basic mitochondrial physiology, but it also links the molecular interactions within these pathways to a variety of diseases. It is one of the first books to combine state-of-the-art reviews regarding basic mitochondrial biology, the role of mitochondrial alterations in different diseases, and the importance of that organelle as a target for pharmacological and non-pharmacological interventions to improve human health. The different chapters highlight the chemical-biological linkages of the mitochondria in context with drug development and clinical applications.
541 ## - IMMEDIATE SOURCE OF ACQUISITION NOTE
Owner UABC ;
Method of acquisition Temporal ;
Date of acquisition 01/01/2021-12/31/2023.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Pharmacology.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Medicinal chemistry.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Medical biochemistry.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Oxidative stress.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Pharmacology/Toxicology.
-- https://scigraph.springernature.com/ontologies/product-market-codes/B21007
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Medicinal Chemistry.
-- https://scigraph.springernature.com/ontologies/product-market-codes/C28000
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Medical Biochemistry.
-- https://scigraph.springernature.com/ontologies/product-market-codes/H35005
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Término temático o nombre geográfico como elemento de entrada Oxidative Stress.
-- https://scigraph.springernature.com/ontologies/product-market-codes/L16070
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Oliveira, Paulo J.
Relator term editor.
Relator code edt
-- http://id.loc.gov/vocabulary/relators/edt
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer Nature eBook
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Printed edition:
International Standard Book Number 9783319733432
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Printed edition:
International Standard Book Number 9783319733456
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Printed edition:
International Standard Book Number 9783030103583
856 40 - ELECTRONIC LOCATION AND ACCESS
Public note Libro electrónico
Uniform Resource Identifier http://148.231.10.114:2048/login?url=https://doi.org/10.1007/978-3-319-73344-9
912 ## -
-- ZDB-2-SBL
912 ## -
-- ZDB-2-SXB
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Libro Electrónico
Existencias
Estado de retiro Colección Ubicación permanente Ubicación actual Fecha de ingreso Total Checkouts Date last seen Número de copia Tipo de material
  Colección de Libros Electrónicos Biblioteca Electrónica Biblioteca Electrónica 01/02/2021   01/02/2021 1 Libro Electrónico

Con tecnología Koha