MARC details
000 -LIDER |
fixed length control field |
04782nam a22005775i 4500 |
001 - CONTROL NUMBER |
control field |
978-3-031-23781-2 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
DE-He213 |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20240207153541.0 |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
fixed length control field |
cr nn 008mamaa |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
230310s2023 sz | s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9783031237812 |
-- |
978-3-031-23781-2 |
050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
QH623 |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
PSF |
Source |
bicssc |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
SCI049000 |
Source |
bisacsh |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
PSF |
Source |
thema |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
Classification number |
571.6 |
Edition number |
23 |
245 10 - TITLE STATEMENT |
Title |
Integrins in Health and Disease |
Medium |
[electronic resource] : |
Remainder of title |
Key Effectors of Cell-Matrix and Cell-Cell Interactions / |
Statement of responsibility, etc. |
edited by Donald Gullberg, Johannes A. Eble. |
250 ## - EDITION STATEMENT |
Edition statement |
1st ed. 2023. |
264 #1 - |
-- |
Cham : |
-- |
Springer International Publishing : |
-- |
Imprint: Springer, |
-- |
2023. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
XII, 472 p. 1 illus. |
Other physical details |
online resource. |
336 ## - |
-- |
text |
-- |
txt |
-- |
rdacontent |
337 ## - |
-- |
computer |
-- |
c |
-- |
rdamedia |
338 ## - |
-- |
online resource |
-- |
cr |
-- |
rdacarrier |
347 ## - |
-- |
text file |
-- |
PDF |
-- |
rda |
490 1# - SERIES STATEMENT |
Series statement |
Biology of Extracellular Matrix, |
International Standard Serial Number |
2191-1959 ; |
Volume/sequential designation |
13 |
500 ## - GENERAL NOTE |
General note |
Acceso multiusuario |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
Part 1: Knockouts and animal models -- Integrins α1β1 and α2β1 - The generalist collagen receptors -- Roles for Integrin α3β1 in Development and Disease -- Part 2: Fibrosis& Cancer -- Integrins: Key targets in tissue fibrosis and tumor stroma -- Integrins in Cardiac Form, Function and Disease -- Integrin 8 and its ligand nephronectin in health and disease -- v integrin-dependent TGF activation in cancer: a brief update -- Part 3: Human disease -- a11b1, a mesenchymal collagen-binding integrin with a central role in tissue- and tumor fibrosis -- Integrins in pathological tissue remodelling of joints -- α4 integrins in immune homeostasis and disease -- β2-integrins in immunity: new roles for old players -- Structure and function of the leukocyte integrin αMβ2 -- Part 4: Integrins in hemostasis, and immune control -- Platelet integrins: Critical mediators of haemostasis and pathological thrombus formation -- Integrins as receptors for bacterial and viral pathogens. |
520 ## - SUMMARY, ETC. |
Summary, etc. |
Integrins are heterodimeric cell surface receptors which anchor cells to different extracellular matrix proteins or act as cell-cell receptors. They play pivotal roles not only across a wide range of physiological processes including tissue morphogenesis, wound healing, and regulation of cell growth, but also in numerous pathological conditions such as autoimmunity, infectious disease, and carcinogenesis. This book aims to provide readers a summary of the most important integrins and their respective biological functions. Readers will learn about knockout- and animal models to study the functionality of key collagen-, laminin-, and nephronectin-binding integrins. Additionally, the role of integrins in pathological tissue remodeling in joints and in developing and diseased cardiac tissue are discussed. Reviews of the current knowledge of the role of integrins in tissue and tumor fibrosis, angiogenesis and tumor progression are an important part of this work. Finally, the book discusses integrins in the context of the immune system, how to target integrin-ligand interactions with antibodies, and the role of integrins as receptors for bacterial and viral cell invasion. Both experienced researchers and clinicians, as well as PhD students who wish to study the extracellular matrix and cell adhesion molecules will find "Integrins in Health and Disease - Key Effectors of Cell-Matrix and Cell-Cell Interactions" authoritative, easily accessible, and vastly informative. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology and the International Society for Matrix Biology. |
541 ## - IMMEDIATE SOURCE OF ACQUISITION NOTE |
Owner |
UABC ; |
Method of acquisition |
Perpetuidad |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Término temático o nombre geográfico como elemento de entrada |
Cell adhesion. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Término temático o nombre geográfico como elemento de entrada |
Cytology. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Término temático o nombre geográfico como elemento de entrada |
Proteins . |
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Término temático o nombre geográfico como elemento de entrada |
Cell Adhesion. |
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Término temático o nombre geográfico como elemento de entrada |
Cell Biology. |
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Término temático o nombre geográfico como elemento de entrada |
Protein Biochemistry. |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Gullberg, Donald. |
Relator term |
editor. |
Relator code |
edt |
-- |
http://id.loc.gov/vocabulary/relators/edt |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Eble, Johannes A. |
Relator term |
editor. |
Relator code |
edt |
-- |
http://id.loc.gov/vocabulary/relators/edt |
710 2# - ADDED ENTRY--CORPORATE NAME |
Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
773 0# - HOST ITEM ENTRY |
Title |
Springer Nature eBook |
776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
Relationship information |
Printed edition: |
International Standard Book Number |
9783031237805 |
776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
Relationship information |
Printed edition: |
International Standard Book Number |
9783031237829 |
776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
Relationship information |
Printed edition: |
International Standard Book Number |
9783031237836 |
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
Uniform title |
Biology of Extracellular Matrix, |
-- |
2191-1959 ; |
Volume number/sequential designation |
13 |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Public note |
Libro electrónico |
Uniform Resource Identifier |
http://libcon.rec.uabc.mx:2048/login?url=https://doi.org/10.1007/978-3-031-23781-2 |
912 ## - |
-- |
ZDB-2-SBL |
912 ## - |
-- |
ZDB-2-SXB |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Libro Electrónico |