Plant-Based Therapeutics, Volume 2 (Registro nro. 276687)

MARC details
000 -LIDER
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001 - CONTROL NUMBER
control field 978-3-031-63681-3
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250516160150.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
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020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9783031636813
-- 978-3-031-63681-3
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number QK
072 #7 - SUBJECT CATEGORY CODE
Subject category code PST
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code SCI011000
Source bisacsh
072 #7 - SUBJECT CATEGORY CODE
Subject category code PST
Source thema
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 580
Edition number 23
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Ross, Ivan A.
Relator term author.
Relator code aut
-- http://id.loc.gov/vocabulary/relators/aut
245 10 - TITLE STATEMENT
Title Plant-Based Therapeutics, Volume 2
Medium [electronic resource] :
Remainder of title The Brassicaceae Family /
Statement of responsibility, etc. by Ivan A. Ross.
250 ## - EDITION STATEMENT
Edition statement 1st ed. 2024.
264 #1 -
-- Cham :
-- Springer Nature Switzerland :
-- Imprint: Springer,
-- 2024.
300 ## - PHYSICAL DESCRIPTION
Extent XXIII, 820 p.
Other physical details online resource.
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-- online resource
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505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Ch01: The History of Brassicaceae Plants -- Ch-02: The Bioactive Components of Brassicaceae -- Ch-03: Chemical Constituents of Brassicaceae -- Ch-04: Nutrigenomics and Metabolomics of the Bioactive Compounds -- ch-05: The Anticarcinogenic Properties of Brassica Vegetables -- ch-06: Neurodegenerative Diseases -- ch-07: Epigenetic Modulation by Isothiocyanates -- ch-08: Breast Cancer -- ch-09: Brain Cancer -- ch-10: Cancer of the Gastrointestinal Tract -- ch-11: Cancer of the Urinary Bladder -- ch-12: Prostate Cancer -- Ch13: Brassica Vegetables and Hypothyroidism -- ch14: Brassicaceae and Viral Diseases -- ch15:Melatonin in Plants and Animals.
520 ## - SUMMARY, ETC.
Summary, etc. For centuries, research has been conducted on the therapeutics of Brassicaceae plants and their health-promoting effects. Cato the Elder (234-149 BCE) documented their properties in his work De agri cultura and recommended using cabbage to compress wounds, swelling, burns, and bone dislocations. For arthritis, he recommended chopped raw cabbage mixed with coriander and cured cabbage mixed with vinegar and honey. In a groundbreaking discovery in the 1990s, scientists at Johns Hopkins University isolated sulforaphane from broccoli, revealing its potent anticancer properties. This naturally occurring compound has proven highly effective, safe, and tolerable and holds immense promise as a chemoprevention agent. It has the potential to combat various cancers, including breast, prostate, gastrointestinal, melanoma, lung, brain, and bladder. But its potential does not stop there. It also shows promise in treating cardiovascular and neurodegenerative diseases and diabetes, offering hope for those affected. The cancer-protecting properties of Brassica plants are mediated through compounds that induce a variety of physiological processes, including antioxidant action, detoxifying enzymes, inducing apoptosis, and cell cycle regulation. Glucosinolate breakdown products can affect several stages of cancer development, including the inhibition of activation enzymes (phase I) and the induction of detoxification enzymes (phase II). Isothiocyanates and indole products formed from glucosinolates regulate cancer cell development by regulating target enzymes, controlling apoptosis, inhibiting angiogenesis, metastasis, and the migration of cancer cells, and blocking the cell cycle. Sulforaphane, found in abundance in broccoli sprouts, plays a crucial role in upregulating the transcriptional activity of specific genes and restoring epigenetic alterations. This is particularly significant as it modifies epigenetic pathways by targeting histone deacetylases and DNA methyltransferases. These modifications, in turn, alter gene transcription and expression, particularly in the case of cancers. This intricate process of gene regulation is a fascinating study area, making broccoli sprouts a compelling component of the 'epigenetic diet.' Sulforaphane induces the cytoprotective enzyme NQO1. The inducible expression of NQO1 is regulated principally through the Keap1-Nrf2-ARE signaling pathway. The activation of the Nrf2-Keap1 signaling pathway heralds the beneficial actions of drugs known to affect Nrf2 signaling, such as dimethyl fumarate, an FDA-approved treatment for multiple sclerosis, and bardoxolone methyl for chronic kidney disease. There is optimism that the overall strategies are moving forward. Sulforaphane-rich broccoli sprout extracts provide one avenue toward this end.
541 ## - IMMEDIATE SOURCE OF ACQUISITION NOTE
Owner UABC ;
Method of acquisition Perpetuidad
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Término temático o nombre geográfico como elemento de entrada Botany.
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Término temático o nombre geográfico como elemento de entrada Physiology.
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Término temático o nombre geográfico como elemento de entrada Plant Science.
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Término temático o nombre geográfico como elemento de entrada Complementary and Alternative Medicine.
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Término temático o nombre geográfico como elemento de entrada Pharmacology.
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Término temático o nombre geográfico como elemento de entrada Medicinal Chemistry.
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Término temático o nombre geográfico como elemento de entrada Agriculture.
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710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer Nature eBook
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Printed edition:
International Standard Book Number 9783031636806
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Printed edition:
International Standard Book Number 9783031636820
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Printed edition:
International Standard Book Number 9783031636837
856 40 - ELECTRONIC LOCATION AND ACCESS
Public note Libro electrónico
Uniform Resource Identifier http://libcon.rec.uabc.mx:2048/login?url=https://doi.org/10.1007/978-3-031-63681-3
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Koha item type Libro Electrónico
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