3D cell-based biosensors in drug discovery programs : microtissue engineering for high throughput screening / William S. Kisaalita.
Tipo de material:
TextoDetalles de publicación: Boca Raton : CRC Press, c2010Descripción: xvii, 386 p. : il. ; 25 cmISBN: 9781420073492 (hardcover : alk. paper); 1420073494 (hardcover : alk. paper)Otro título: Three-dimensional cell-based biosensors in drug discovery programsTema(s): Pharmaceutical biotechnology | Biosensors | High throughput screening (Drug development) | Biosensing Techniques -- methods | Cells, Cultured | Drug Discovery | BiosensoresClasificación CDD: 615/.19 Clasificación LoC:RS380 | .K537 2010QT36 K58 2010| Tipo de ítem | Biblioteca actual | Colección | Signatura | Copia número | Estado | Fecha de vencimiento | Código de barras |
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Libro
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Biblioteca Central Ensenada | Acervo General | RS380 K58 2010 (Browse shelf(Abre debajo)) | 1 | Disponible | ENS068103 |
Navegando Biblioteca Central Ensenada Estantes, Código de colección: Acervo General Cerrar el navegador de estanterías (Oculta el navegador de estanterías)
| RS192 M52 2001 Microbial fundamentals of biotechnology : | RS380 B56 Biotechnology and pharmacy / | RS380 D63 2011 Healthcare biotechnology : | RS380 K58 2010 3D cell-based biosensors in drug discovery programs : | RS403 B87 2003 V.2 Burger's medicinal chemistry [and] drug discovery / | RS403 C35 2007 Química fina farmacéutica / | RS403 P38 2001 An introduction to medicinal chemistry / |
Incluye referencias bibliográficas e índice.
Biosensors and bioassays -- Target-driven drug discovery -- Comparative transcriptional profiling and proteomics -- Comparative structure and function -- Chemical microenvironmental factors -- Spatial and temporal microenvironmental factors -- Material physical property and force microenvironmental factors -- Proteomics as a promising tool in the search for 3D biomarkers -- Readout present and near future -- Ready-to-use commercial 3D plates -- Challenges to adopting 3D cultures in HTS programs -- Cases for 3D cultures in drug discovery -- Ideal case study design.
"This book is based upon cutting-edge research conducted in the authors lab (Cellular Bioengineering), which over the past decade has developed a number of sophisticated techniques to facilitate use of 3D cell based assays or biosensors. This book uses data from peer-reviewed publications to conclusively justify use of 3D cell cultures in cell-based biosensors (assays) for (HTS). The majority of assays performed in accelerated drug discovery processes are biochemical in nature, but there is a growing demand for live cell-based assays. Unlike biochemical ones, cellular assays are functional approximations of in vivo biological conditions and can provide more biologically relevant information"--Provided by publisher.
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