Tissue engineering and artificial organs / edited by Joseph D. Bronzino.

Volume of the 3rd ed. of The biomedical engineering handbook.

Incluye referencias bibliográficas e índice.

Sect. I. Molecular biology. Historical perspective and basics of molecular biology -- Systems and technology involving bacteria -- Recombinant DNA technology using mammalian cells -- sect. II. Transport phenomena and biomimetic systems. Biomimetic systems -- Diffusional processes and engineering design -- Microvascular heat transfer -- Perfusion effects and hydrodynamics -- Animal surrogate systems -- Arterial wall mass transport: the possible role of blood phase resistance in the localization of arterial disease -- Control of the microenvironment -- Interstitial transport in the brain: principles for local drug delivery -- sect. III. Biotechnology. Tools for genome analysis -- Vaccine production -- Protein ngineering -- Metabolic engineering -- Monoclonal antibodies and their engineered fragments.

Biomolecular engineering in oligonucleotide applications -- Gene therapy -- Bio-nanorobotics: state of the art and future challenges -- sect. IV. Bionanotechnology. DNA as a scaffold for nano-structure assembly -- Directed evolution of proteins for device applications -- Semiconductor quantum dots for molecular and cellular imaging -- Bionanotechnology for bioanalysis -- Nano-hydroxyapatite for biomedical applications -- Nanotechnology provides new tools for biomedical optics -- Nanomaterials perspectives and possibilities in nanomedicine -- Biomedical nanoengineering for nanomedicine -- Physiogenomics: integrating systems engineering and nanotechnology for personalized medicine -- Bionanotechnology patenting: challenges and opportunities -- sect. V. Tissue engineering. Fundamentals of stem cell tissue engineering -- Growth factors and morphogens: signals for tissue engineering -- Extracellular matrix: structure, function, and applications to tissue engineering.

Mechanical forces on cells -- Cell adhesion -- Cell migration -- Inflammatory and immune responses to tissue engineered devices -- Polymeric scaffolds for tissue engineering applications -- Calcium phosphate ceramics for bone tissue engineering -- Biomimetic materials -- Nanocomposite scaffolds for tissue engineering -- Roles of thermodynamic state and molecular mobility in biopreservation -- Drug delivery -- Gene therapy -- Tissue engineering bioreactors -- Animal models for evaluation of tissue-engineered orthopedic implants -- The regulation of engineered tissues: emerging approaches -- Bioengineering of human skin substitutes -- Nerve regeneration: tissue engineering strategies -- Gene therapy and tissue engineering based on muscle-derived stem cells: potential for musculoskeletal tissue regeneration and repair -- Tissue engineering applications -- bone -- Cartilage tissue engineering -- Tissue engineering of the tempormandibular joint -- Engineering smoot muscle.

Esophagus: a tissue engineering challenge -- Tissue engineered vascular grafts -- Cardiac tissue engineering: matching native architecture and function to develop safe and efficient therapy -- Tissue engineering of heart valves -- Tissue engineering, stem cells and cloning for the regeneration of urologic organs -- Hepatic tissue engineering for adjunct and temporary liver support -- Tissue engineering of renal replacement therapy -- The bioengineering of dental tissues -- Tracheal tissue engineering -- sect. VI. Prostheses and artificial organs. Artificial heart and circulatory assist devices -- Cardiac valve prostheses -- Vascular grafts -- Artificial lungs and blood-gas exchange devices -- Artificial kidney -- Peritoneal dialysis equipment -- Therapeutic apheresis and blood fractionation -- Liver support systems -- Artificial pancreas -- Nerve guidance channels -- Tracheal, laryngeal, and esophageal replacement devices -- Artificial blood -- Artificial skin and dermal equivalents -- sect. VII. Ethics. Beneficence, nonmaleficence, and medical technology -- Ethical isseus related to clinical research.

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