Recoding: Expansion of Decoding Rules Enriches Gene Expression [recurso electrónico] / edited by John F. Atkins, Raymond F. Gesteland.

Por: Atkins, John F [editor.]Colaborador(es): Gesteland, Raymond F [editor.] | SpringerLink (Online service)Tipo de material: TextoTextoSeries Nucleic Acids and Molecular Biology ; 24Editor: New York, NY : Springer New York : Imprint: Springer, 2010Descripción: XX, 466p. 156 illus., 63 illus. in color. online resourceTipo de contenido: text Tipo de medio: computer Tipo de portador: online resourceISBN: 9780387893822Tema(s): Life sciences | Human genetics | Biochemistry | Cytology | Microbiology | Life Sciences | Microbiology | Human Genetics | Biochemistry, general | Cell BiologyFormatos físicos adicionales: Printed edition:: Sin títuloClasificación CDD: 579 Clasificación LoC:QR1-502Recursos en línea: Libro electrónicoTexto
Contenidos:
Redefinition -- Selenocysteine Biosynthesis, Selenoproteins, and Selenoproteomes -- Reprogramming the Ribosome for Selenoprotein Expression: RNA Elements and Protein Factors -- Translation of UAG as Pyrrolysine -- Specification of Standard Amino Acids by Stop Codons -- Ribosome “Skipping”: “Stop-Carry On” or “StopGo” Translation -- Recoding Therapies for Genetic Diseases -- Frameshifting – Redirection of Linear Readout -- Pseudoknot-Dependent Programmed —1 Ribosomal Frameshifting: Structures, Mechanisms and Models -- Programmed —1 Ribosomal Frameshift in the Human Immunodeficiency Virus of Type 1 -- Ribosomal Frameshifting in Decoding Plant Viral RNAs -- Programmed Frameshifting in Budding Yeast -- Recoding in Bacteriophages -- Programmed Ribosomal ?1 Frameshifting as a Tradition: The Bacterial Transposable Elements of the IS3 Family -- Autoregulatory Frameshifting in Antizyme Gene Expression Governs Polyamine Levels from Yeast to Mammals -- Sequences Promoting Recoding Are Singular Genomic Elements -- Mutants That Affect Recoding -- The E Site and Its Importance for Improving Accuracy and Preventing Frameshifts -- Discontiguity -- Translational Bypassing – Peptidyl-tRNA Re-pairing at Non-overlapping Sites -- trans-Translation -- Transcription Slippage -- Transcript Slippage and Recoding -- Computational Resources for Studying Recoding.
En: Springer eBooksResumen: The dynamic nature of decoding the information in messenger RNA was unanticipated at the time the genetic code was first deciphered. We now know that both the meaning of individual codons and the framing of the readout process can be modified by information in specific messenger RNAs. This book describes this "Recoding" phenomenon, revealing the diversity of an additional layer of information in mRNAs that serves to enrich the expression of genes. Knowledge of recoding is essential for understanding the organization and expression of genes in viruses and all organisms ranging from bacteria to archeae to plants to humans, making Recoding pertinent to all biological sciences.
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Existencias
Tipo de ítem Biblioteca actual Colección Signatura Copia número Estado Fecha de vencimiento Código de barras
Libro Electrónico Biblioteca Electrónica
Colección de Libros Electrónicos QR1 -502 (Browse shelf(Abre debajo)) 1 No para préstamo 370329-2001

Redefinition -- Selenocysteine Biosynthesis, Selenoproteins, and Selenoproteomes -- Reprogramming the Ribosome for Selenoprotein Expression: RNA Elements and Protein Factors -- Translation of UAG as Pyrrolysine -- Specification of Standard Amino Acids by Stop Codons -- Ribosome “Skipping”: “Stop-Carry On” or “StopGo” Translation -- Recoding Therapies for Genetic Diseases -- Frameshifting – Redirection of Linear Readout -- Pseudoknot-Dependent Programmed —1 Ribosomal Frameshifting: Structures, Mechanisms and Models -- Programmed —1 Ribosomal Frameshift in the Human Immunodeficiency Virus of Type 1 -- Ribosomal Frameshifting in Decoding Plant Viral RNAs -- Programmed Frameshifting in Budding Yeast -- Recoding in Bacteriophages -- Programmed Ribosomal ?1 Frameshifting as a Tradition: The Bacterial Transposable Elements of the IS3 Family -- Autoregulatory Frameshifting in Antizyme Gene Expression Governs Polyamine Levels from Yeast to Mammals -- Sequences Promoting Recoding Are Singular Genomic Elements -- Mutants That Affect Recoding -- The E Site and Its Importance for Improving Accuracy and Preventing Frameshifts -- Discontiguity -- Translational Bypassing – Peptidyl-tRNA Re-pairing at Non-overlapping Sites -- trans-Translation -- Transcription Slippage -- Transcript Slippage and Recoding -- Computational Resources for Studying Recoding.

The dynamic nature of decoding the information in messenger RNA was unanticipated at the time the genetic code was first deciphered. We now know that both the meaning of individual codons and the framing of the readout process can be modified by information in specific messenger RNAs. This book describes this "Recoding" phenomenon, revealing the diversity of an additional layer of information in mRNAs that serves to enrich the expression of genes. Knowledge of recoding is essential for understanding the organization and expression of genes in viruses and all organisms ranging from bacteria to archeae to plants to humans, making Recoding pertinent to all biological sciences.

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