Principles of Clinical Cancer Genetics [recurso electrónico] : A Handbook from the Massachusetts General Hospital / edited by Daniel C. Chung, Daniel A. Haber.

Por: Chung, Daniel C [editor.]Colaborador(es): Haber, Daniel A [editor.] | SpringerLink (Online service)Tipo de material: TextoTextoEditor: Boston, MA : Springer US : Imprint: Springer, 2010Descripción: X, 227p. 48 illus., 46 illus. in color. online resourceTipo de contenido: text Tipo de medio: computer Tipo de portador: online resourceISBN: 9780387938462Tema(s): Medicine | Human genetics | Oncology | Medicine & Public Health | Oncology | Human GeneticsFormatos físicos adicionales: Printed edition:: Sin títuloClasificación CDD: 616.994 Clasificación LoC:RC254-282Recursos en línea: Libro electrónicoTexto
Contenidos:
Basic Principles of Cancer Genetics -- Principles of Cancer Genetic Counseling and Genetic Testing -- Genetics of Hereditary Breast Cancer -- Surgical Management of Hereditary Breast and Ovarian Cancer -- Hereditary Colon Cancer: Colonic Polyposis Syndromes -- Hereditary Colon Cancer: Lynch Syndrome -- Hereditary Pancreatic Cancer -- Hereditary Diffuse Gastric Cancer -- Familial Renal Cell Cancers and Pheochromocytomas -- Familial Atypical Mole Melanoma (FAMM) Syndrome -- Multiple Endocrine Neoplasia -- Pediatric Malignancies: Retinoblastoma and Wilms’ Tumor -- Neurofibromatosis and Schwannomatosis -- The HapMap Project and Low-Penetrance Cancer Susceptibility Alleles -- Somatic Genetic Alterations and Implications for Targeted Therapies in Cancer (GIST, CML, Lung Cancer).
En: Springer eBooksResumen: Advances in genetics are transforming estimates of an individual’s risk of developing cancer and approaches to prevention and management of cancer in those who may have increased susceptibility. Identifying and caring for patients with hereditary cancer syndromes and their family members present a complex clinical, scientific and social challenge. This textbook, by leading experts at Massachusetts General Hospital Cancer Center, highlights the current understanding of the genetics of hereditary cancers of the breast, ovary, colorectum, stomach, pancreas, kidney, skin, and endocrine organs. Practical guidelines for the use of genetic testing, cancer screening and surveillance, prophylactic surgery, and promising targeted therapeutic agents are discussed. In addition, ongoing research involving genome-wide screens to identify novel modest risk-associated genetic loci are explored, along with new approaches to the application of genetic markers in guiding therapeutic options.
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Existencias
Tipo de ítem Biblioteca actual Colección Signatura Copia número Estado Fecha de vencimiento Código de barras
Libro Electrónico Biblioteca Electrónica
Colección de Libros Electrónicos RC254 -282 (Browse shelf(Abre debajo)) 1 No para préstamo 370364-2001

Basic Principles of Cancer Genetics -- Principles of Cancer Genetic Counseling and Genetic Testing -- Genetics of Hereditary Breast Cancer -- Surgical Management of Hereditary Breast and Ovarian Cancer -- Hereditary Colon Cancer: Colonic Polyposis Syndromes -- Hereditary Colon Cancer: Lynch Syndrome -- Hereditary Pancreatic Cancer -- Hereditary Diffuse Gastric Cancer -- Familial Renal Cell Cancers and Pheochromocytomas -- Familial Atypical Mole Melanoma (FAMM) Syndrome -- Multiple Endocrine Neoplasia -- Pediatric Malignancies: Retinoblastoma and Wilms’ Tumor -- Neurofibromatosis and Schwannomatosis -- The HapMap Project and Low-Penetrance Cancer Susceptibility Alleles -- Somatic Genetic Alterations and Implications for Targeted Therapies in Cancer (GIST, CML, Lung Cancer).

Advances in genetics are transforming estimates of an individual’s risk of developing cancer and approaches to prevention and management of cancer in those who may have increased susceptibility. Identifying and caring for patients with hereditary cancer syndromes and their family members present a complex clinical, scientific and social challenge. This textbook, by leading experts at Massachusetts General Hospital Cancer Center, highlights the current understanding of the genetics of hereditary cancers of the breast, ovary, colorectum, stomach, pancreas, kidney, skin, and endocrine organs. Practical guidelines for the use of genetic testing, cancer screening and surveillance, prophylactic surgery, and promising targeted therapeutic agents are discussed. In addition, ongoing research involving genome-wide screens to identify novel modest risk-associated genetic loci are explored, along with new approaches to the application of genetic markers in guiding therapeutic options.

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