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Gene Expression and Its Discontents [recurso electrónico] : The Social Production of Chronic Disease / by Rodrick Wallace, Deborah Wallace.

Por: Wallace, Rodrick [author.]Colaborador(es): Wallace, Deborah [author.] | SpringerLink (Online service)Tipo de material: Texto

TextoEditor: New York, NY : Springer New York, 2010Descripción: X, 230p. 16 illus. online resourceTipo de contenido: text Tipo de medio: computer Tipo de portador: online resourceISBN: 9781441914828Tema(s): Medicine | Human genetics | Epidemiology | Bioinformatics | Biomedicine | Human Genetics | Computational Biology/Bioinformatics | Public Health/Gesundheitswesen | EpidemiologyFormatos físicos adicionales: Printed edition:: Sin títuloClasificación CDD: 611.01816 | 599.935 Clasificación LoC:RB155-155.8QH431Recursos en línea: Libro electrónico Texto

Contenidos:

Models of development -- Groupoid symmetries -- Epigenetic catalysis -- Developmental disorders -- An interim perspective -- The obesity pandemic in the US -- Coronary heart disease in the US -- Cancer: a developmental perspective -- Autoimmune disorders -- Demoralization and obesity in Upper Manhattan -- Death at an early age: AIDS and related mortality in New York City -- Final thoughts -- Mathematical appendix -- References.

En: Springer eBooksResumen: A cognitive paradigm for gene expression, via the asymptotic limit theorems of information theory, allows better understanding of how embedding context affects the development of organisms. In sum, epigenetic information sources act as tunable catalysts, directing ontogeny into characteristic pathways, a perspective having important implications for epigenetic epidemiology. The authors show how environmental stressors, in a large sense, can induce a broad spectrum of developmental dysfunctions, and examine a number of pandemic chronic diseases, using U.S. data at different scales on the effects of the legacy of slavery compounded by accelerating industrial and urban decay. Developmental disorders, broadly taken, are unlikely to respond to medical interventions in the face of serious, persistent individual and community stress. In particular, drugs powerful enough to affect deleterious epigenetic programming will likely trigger side effects leading to shortened lifespan. The address of pandemic chronic disease requires significant large-scale changes in public policy and resource allocation.

Existencias ( 1 )
Notas de título ( 3 )

Existencias
Tipo de ítem	Biblioteca actual	Colección	Signatura	Copia número	Estado	Fecha de vencimiento	Código de barras
Libro Electrónico	Biblioteca Electrónica	Colección de Libros Electrónicos	RB155 -155.8 (Browse shelf(Abre debajo))	1	No para préstamo		371355-2001

A cognitive paradigm for gene expression, via the asymptotic limit theorems of information theory, allows better understanding of how embedding context affects the development of organisms. In sum, epigenetic information sources act as tunable catalysts, directing ontogeny into characteristic pathways, a perspective having important implications for epigenetic epidemiology. The authors show how environmental stressors, in a large sense, can induce a broad spectrum of developmental dysfunctions, and examine a number of pandemic chronic diseases, using U.S. data at different scales on the effects of the legacy of slavery compounded by accelerating industrial and urban decay. Developmental disorders, broadly taken, are unlikely to respond to medical interventions in the face of serious, persistent individual and community stress. In particular, drugs powerful enough to affect deleterious epigenetic programming will likely trigger side effects leading to shortened lifespan. The address of pandemic chronic disease requires significant large-scale changes in public policy and resource allocation.