mTOR Pathway and mTOR Inhibitors in Cancer Therapy [recurso electrónico] / edited by Vitaly A. Polunovsky, Peter J. Houghton.
Tipo de material: TextoSeries Cancer Drug Discovery and DevelopmentEditor: Totowa, NJ : Humana Press : Imprint: Humana Press, 2010Descripción: XII, 304 p. online resourceTipo de contenido: text Tipo de medio: computer Tipo de portador: online resourceISBN: 9781603272711Tema(s): Medicine | Oncology | Toxicology | Cytology | Biomedicine | Cancer Research | Cell Biology | Pharmacology/ToxicologyFormatos físicos adicionales: Printed edition:: Sin títuloClasificación CDD: 614.5999 Clasificación LoC:RC261-271Recursos en línea: Libro electrónicoTipo de ítem | Biblioteca actual | Colección | Signatura | Copia número | Estado | Fecha de vencimiento | Código de barras |
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Libro Electrónico | Biblioteca Electrónica | Colección de Libros Electrónicos | RC261 -271 (Browse shelf(Abre debajo)) | 1 | No para préstamo | 372521-2001 |
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RC261 -271 Environment and Breast Cancer | RC261 -271 Insulin Resistance and Cancer | RC261 -271 Alcohol and Cancer | RC261 -271 mTOR Pathway and mTOR Inhibitors in Cancer Therapy | RC261 -271 Cancer and IgE | RC261 -271 Protein Kinase C in Cancer Signaling and Therapy | RC261 -271 Bladder Tumors: |
mTORC1: A Signaling Integration Node Involved in Cell Growth -- The Regulation of the IGF-1/mTOR Pathway by the p53 Tumor Suppressor Gene Functions -- mTOR Signaling in Angiogenesis -- mTORC1 Signaling and Hypoxia -- mTOR Signaling in Glioblastoma: Lessons Learned from Bench to Bedside -- mTOR and Cancer Therapy: General Principles -- mTOR and Cancer Therapy: Clinical Development and Novel Prospects -- Drug Combinations as a Therapeutic Approach for mTORC1 Inhibitors in Human Cancer -- Downstream Targets of mTORC1 -- Downstream of mTOR: Translational Control of Cancer -- Genome-Wide Analysis of Translational Control -- Translational Control of Cancer: Implications for Targeted Therapy -- Downstream from mTOR: Therapeutic Approaches to Targeting the eIF4F Translation Initiation Complex.
mTOR Pathway and mTOR Inhibitors in Cancer Therapy provides an up-to-date survey of the rapidly advancing field of cancer therapy. Our understanding of the mechanisms involved in cancer genesis and progression underwent unprecedented expansion during the last decade, opening a new era of cancer treatment – targeted therapy. The surge in this area results in no small part from studies conducted jointly by basic health scientists and clinical investigators. It is our hope that this book will help foster even further collaboration between investigators in these two disciplines. In this work, experts in TOR signaling have contributed in two thematic areas: mTOR Signaling and Cancer Therapy (chapters 1 - 8) and Therapeutic Targeting Downstream of mTOR (chapter 9 – 13). All chapters of mTOR Pathway and mTOR Inhibitors in Cancer Therapy are completely new or have been extensively updated by their authors; and we are indebted to all authors who have exemplified the links between these 2 thematic areas.
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