The Extracellular Matrix: an Overview [recurso electrónico] / edited by Robert P. Mecham.

Por: Mecham, Robert P [editor.]Colaborador(es): SpringerLink (Online service)Tipo de material: TextoTextoSeries Biology of Extracellular MatrixEditor: Berlin, Heidelberg : Springer Berlin Heidelberg, 2011Descripción: XIV, 426 p. online resourceTipo de contenido: text Tipo de medio: computer Tipo de portador: online resourceISBN: 9783642165559Tema(s): Life sciences | Medicine | Biochemistry | Cytology | Life Sciences | Cell Biology | Protein Science | Molecular MedicineFormatos físicos adicionales: Printed edition:: Sin títuloClasificación CDD: 571.6 Clasificación LoC:QH573-671Recursos en línea: Libro electrónicoTexto
Contenidos:
An overview of extracellular matrix structure and function --  Fibronectin and other adhesive glycoproteins --  Collagen: suprastructures and collagen fibril assembly.-  Asement membrane; Hyaluronan and the Aggregating Proteoglycans -- The small, leucine-rich proteoglycans -- Microfibrils and fibrillin -- Elastin -- Lysyl oxidase and lysyl oxidase-like enzymes -- The Fibulins -- Matricellular proteins.
En: Springer eBooksResumen: Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment.  Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.
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Existencias
Tipo de ítem Biblioteca actual Colección Signatura Copia número Estado Fecha de vencimiento Código de barras
Libro Electrónico Biblioteca Electrónica
Colección de Libros Electrónicos QH573 -671 (Browse shelf(Abre debajo)) 1 No para préstamo 375341-2001

An overview of extracellular matrix structure and function --  Fibronectin and other adhesive glycoproteins --  Collagen: suprastructures and collagen fibril assembly.-  Asement membrane; Hyaluronan and the Aggregating Proteoglycans -- The small, leucine-rich proteoglycans -- Microfibrils and fibrillin -- Elastin -- Lysyl oxidase and lysyl oxidase-like enzymes -- The Fibulins -- Matricellular proteins.

Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment.  Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.

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