The Extracellular Matrix: an Overview [recurso electrónico] / edited by Robert P. Mecham.
Tipo de material: TextoSeries Biology of Extracellular MatrixEditor: Berlin, Heidelberg : Springer Berlin Heidelberg, 2011Descripción: XIV, 426 p. online resourceTipo de contenido: text Tipo de medio: computer Tipo de portador: online resourceISBN: 9783642165559Tema(s): Life sciences | Medicine | Biochemistry | Cytology | Life Sciences | Cell Biology | Protein Science | Molecular MedicineFormatos físicos adicionales: Printed edition:: Sin títuloClasificación CDD: 571.6 Clasificación LoC:QH573-671Recursos en línea: Libro electrónicoTipo de ítem | Biblioteca actual | Colección | Signatura | Copia número | Estado | Fecha de vencimiento | Código de barras |
---|---|---|---|---|---|---|---|
Libro Electrónico | Biblioteca Electrónica | Colección de Libros Electrónicos | QH573 -671 (Browse shelf(Abre debajo)) | 1 | No para préstamo | 375341-2001 |
Navegando Biblioteca Electrónica Estantes, Código de colección: Colección de Libros Electrónicos Cerrar el navegador de estanterías (Oculta el navegador de estanterías)
QH573 -671 Cellular Peptide Hormone Synthesis and Secretory Pathways | QH573 -671 Extracellular Nucleic Acids | QH573 -671 Sensory and Metabolic Control of Energy Balance | QH573 -671 The Extracellular Matrix: an Overview | QH573 -671 Glycans in Diseases and Therapeutics | QH573 -671 Extracellular Matrix Degradation | QH573 -671 Mechanosensing Biology |
An overview of extracellular matrix structure and function -- Fibronectin and other adhesive glycoproteins -- Collagen: suprastructures and collagen fibril assembly.- Asement membrane; Hyaluronan and the Aggregating Proteoglycans -- The small, leucine-rich proteoglycans -- Microfibrils and fibrillin -- Elastin -- Lysyl oxidase and lysyl oxidase-like enzymes -- The Fibulins -- Matricellular proteins.
Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.
19