Regulation of Cytokine Gene Expression in Immunity and Diseases [recurso electrónico] / edited by Xiaojing Ma.

Colaborador(es): Ma, Xiaojing [editor.] | SpringerLink (Online service)Tipo de material: TextoTextoSeries Advances in Experimental Medicine and Biology ; 941Editor: Dordrecht : Springer Netherlands : Imprint: Springer, 2016Descripción: VIII, 225 p. 23 illus., 22 illus. in color. online resourceTipo de contenido: text Tipo de medio: computer Tipo de portador: online resourceISBN: 9789402409215Tema(s): Medicine | Gene expression | Immunology | Cytokines | Growth factors | Cell biology | Biomedicine | Immunology | Gene Expression | Cytokines and Growth Factors | Cell BiologyFormatos físicos adicionales: Printed edition:: Sin títuloClasificación CDD: 616.079 Clasificación LoC:QR180-189.5Recursos en línea: Libro electrónicoTexto
Contenidos:
Regulation of IFN-? expression -- Regulation of The interleukin-1 family -- Regulation of IL-4 Expression in Immunity and Diseases -- Regulation of IL-6 in immunity and diseases -- Regulation of Interleukin-10 Expression -- Regulation of Interleukin-12 Production in Antigen-Presenting Cells -- Regulation of Interleukin-17 production -- Regulation of interleukin-23 expression in health and disease -- Regulation and immune function of IL-27 -- The immunobiology of Interleukin-35 and its regulation and gene expression.
En: Springer eBooksResumen: This book explores the major cytokines, such as IL-1 and IFN-?, with respect to the regulation of their gene expression and protein production in specific immune cell types. It discusses both healthy physiological settings and in pathological situations in which the expression of some cytokines could be dysregulated, resulting in either immunodeficiency or exacerbated inflammatory sequelae in animal models as well as in human patients. Cytokines are important regulators of immune responses that require the highly coordinated participation and communication of multiple cell types. The expression of cytokines by various producer cell types is therefore carefully regulated in response to environmental cues at multiple levels: transcription, translation and posttranslational modification. Presenting cutting-edge advances in our understanding of the regulation of cytokine expression, this book is a valuable resource for anyone involved or interested in immune regulation.
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Regulation of IFN-? expression -- Regulation of The interleukin-1 family -- Regulation of IL-4 Expression in Immunity and Diseases -- Regulation of IL-6 in immunity and diseases -- Regulation of Interleukin-10 Expression -- Regulation of Interleukin-12 Production in Antigen-Presenting Cells -- Regulation of Interleukin-17 production -- Regulation of interleukin-23 expression in health and disease -- Regulation and immune function of IL-27 -- The immunobiology of Interleukin-35 and its regulation and gene expression.

This book explores the major cytokines, such as IL-1 and IFN-?, with respect to the regulation of their gene expression and protein production in specific immune cell types. It discusses both healthy physiological settings and in pathological situations in which the expression of some cytokines could be dysregulated, resulting in either immunodeficiency or exacerbated inflammatory sequelae in animal models as well as in human patients. Cytokines are important regulators of immune responses that require the highly coordinated participation and communication of multiple cell types. The expression of cytokines by various producer cell types is therefore carefully regulated in response to environmental cues at multiple levels: transcription, translation and posttranslational modification. Presenting cutting-edge advances in our understanding of the regulation of cytokine expression, this book is a valuable resource for anyone involved or interested in immune regulation.

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