Lung Cancer and Personalized Medicine [recurso electrónico] : Current Knowledge and Therapies / edited by Aamir Ahmad, Shirish Gadgeel.

Colaborador(es): Ahmad, Aamir [editor.] | Gadgeel, Shirish [editor.] | SpringerLink (Online service)Tipo de material: TextoTextoSeries Advances in Experimental Medicine and Biology ; 893Editor: Cham : Springer International Publishing : Imprint: Springer, 2016Descripción: XIII, 228 p. 26 illus., 14 illus. in color. online resourceTipo de contenido: text Tipo de medio: computer Tipo de portador: online resourceISBN: 9783319242231Tema(s): Medicine | Cancer research | Molecular biology | Internal medicine | Oncology | Biomedicine | Cancer Research | Molecular Medicine | Internal Medicine | OncologyFormatos físicos adicionales: Printed edition:: Sin títuloClasificación CDD: 614.5999 Clasificación LoC:RC261-271Recursos en línea: Libro electrónicoTexto
Contenidos:
1 Lung Cancer Statistics -- 2 Epidemiology of Lung Cancer -- 3 Lung Cancer In Never Smokers -- 4 Immune Therapy -- 5 Anti-angiogenesis in personalized therapy of lung cancer -- 6 Target therapy in Lung Cancer -- 7 Mechanisms of Resistance to EGFR Tyrosine Kinase Inhibitors and Therapeutic Approaches: an update -- 8 KRAS-Mutant Lung Cancers in the Era of Targeted Therapy -- 9 Anaplastic Lymphoma Kinase (ALK) Signaling in Lung Cancer -- 10 Chemotherapy Resistance in Lung Cancer -- 11 Current state of metal-based drugs for the efficient therapy of lung cancers and lung metastases.
En: Springer eBooksResumen: This, the first of two volumes on personalized medicine in lung cancer, touches on the core issues related to the understanding of lung cancer´statistics and epidemiology of lung cancer?along with the incidence of lung cancer in non-smokers. A major focus of this volume is the state of current therapies against lung cancer?immune, targeted therapies against EGFR TKIs, KRAS, ALK, angiogenesis; the associated challenges, especially resistance mechanisms; and recent progress in targeted drug development based on metal chemistry. Chapters are written by some of the leading experts in the field, who provide a better understanding of lung cancer, the factors that make it lethal, and current research focused on developing personalized treatment plans. With a unique mix of topics, this volume summarizes the current state-of-knowledge on lung cancer and the available therapies.
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1 Lung Cancer Statistics -- 2 Epidemiology of Lung Cancer -- 3 Lung Cancer In Never Smokers -- 4 Immune Therapy -- 5 Anti-angiogenesis in personalized therapy of lung cancer -- 6 Target therapy in Lung Cancer -- 7 Mechanisms of Resistance to EGFR Tyrosine Kinase Inhibitors and Therapeutic Approaches: an update -- 8 KRAS-Mutant Lung Cancers in the Era of Targeted Therapy -- 9 Anaplastic Lymphoma Kinase (ALK) Signaling in Lung Cancer -- 10 Chemotherapy Resistance in Lung Cancer -- 11 Current state of metal-based drugs for the efficient therapy of lung cancers and lung metastases.

This, the first of two volumes on personalized medicine in lung cancer, touches on the core issues related to the understanding of lung cancer´statistics and epidemiology of lung cancer?along with the incidence of lung cancer in non-smokers. A major focus of this volume is the state of current therapies against lung cancer?immune, targeted therapies against EGFR TKIs, KRAS, ALK, angiogenesis; the associated challenges, especially resistance mechanisms; and recent progress in targeted drug development based on metal chemistry. Chapters are written by some of the leading experts in the field, who provide a better understanding of lung cancer, the factors that make it lethal, and current research focused on developing personalized treatment plans. With a unique mix of topics, this volume summarizes the current state-of-knowledge on lung cancer and the available therapies.

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