Judah Folkman [electronic resource] : A Biography / by Domenico Ribatti.

Por: Ribatti, Domenico [author.]Colaborador(es): SpringerLink (Online service)Tipo de material: TextoTextoEditor: Cham : Springer International Publishing : Imprint: Springer, 2018Edición: 1st ed. 2018Descripción: VIII, 124 p. 29 illus., 16 illus. in color. online resourceTipo de contenido: text Tipo de medio: computer Tipo de portador: online resourceISBN: 9783319926339Tema(s): Medicine | Cell biology | Biology-History | Biomedicine, general | Cell Biology | History of BiologyFormatos físicos adicionales: Printed edition:: Sin título; Printed edition:: Sin título; Printed edition:: Sin títuloClasificación CDD: 610 Clasificación LoC:R-RZRecursos en línea: Libro electrónicoTexto
Contenidos:
Biographic profile -- Development of assays to study angiogenesis -- Tumor angiogenesis -- The discovery of angiogenic factors -- Anti-angiogenesis -- Concluding remarks -- References -- Publications of Judah Folkman (2014-1956). Index.
En: Springer Nature eBookResumen: The aim if this book is to analyze the scientific biography of Judah Folkman, one of the most important scientist of the last century. More 50 years ago, Folkman found a revolutionary new way to think about cancer. Blood supply, Folkman hypothesized, was the key to tumor growth. Without new blood vessels, tumors simply did not thrive. In 1971, Folkman published his theory of angiogenesis in the "New England Journal of Medicine". Angiogenesis, the formation and recruitment of new blood vessels, is necessary for tumor growth. Critics of the theory were silenced over time as Folkman and his colleagues reported the first purified angiogenic molecule, the first angiogenesis inhibitor and proposed the concept of angiogenic disease. The mechanism of angiogenesis is now a worldwide field of investigation. Over the years, Folkman and a growing team of researchers have isolated the proteins and unraveled the processes that regulate angiogenesis. Meanwhile, a new generation of angiogenesis research has emerged as well, widening the field into new areas of human disease and deepening it to examine the underlying biological processes responsible for those diseases.
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Biographic profile -- Development of assays to study angiogenesis -- Tumor angiogenesis -- The discovery of angiogenic factors -- Anti-angiogenesis -- Concluding remarks -- References -- Publications of Judah Folkman (2014-1956). Index.

The aim if this book is to analyze the scientific biography of Judah Folkman, one of the most important scientist of the last century. More 50 years ago, Folkman found a revolutionary new way to think about cancer. Blood supply, Folkman hypothesized, was the key to tumor growth. Without new blood vessels, tumors simply did not thrive. In 1971, Folkman published his theory of angiogenesis in the "New England Journal of Medicine". Angiogenesis, the formation and recruitment of new blood vessels, is necessary for tumor growth. Critics of the theory were silenced over time as Folkman and his colleagues reported the first purified angiogenic molecule, the first angiogenesis inhibitor and proposed the concept of angiogenic disease. The mechanism of angiogenesis is now a worldwide field of investigation. Over the years, Folkman and a growing team of researchers have isolated the proteins and unraveled the processes that regulate angiogenesis. Meanwhile, a new generation of angiogenesis research has emerged as well, widening the field into new areas of human disease and deepening it to examine the underlying biological processes responsible for those diseases.

UABC ; Temporal ; 01/01/2021-12/31/2023.

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