A Scientific Approach to Improving Animal Research in Biomedicine [electronic resource] : Giving Animals a Chance / by Bradley K. Weiner.

Por: Weiner, Bradley K [author.]Colaborador(es): SpringerLink (Online service)Tipo de material: TextoTextoEditor: Cham : Springer International Publishing : Imprint: Springer, 2023Edición: 1st ed. 2023Descripción: XIII, 62 p. 2 illus., 1 illus. in color. online resourceTipo de contenido: text Tipo de medio: computer Tipo de portador: online resourceISBN: 9783031246777Tema(s): Biology -- Technique | Animal welfare -- Moral and ethical aspects | Medicine -- Research | Biology -- Research | Experimental Organisms | Animal Ethics | Biomedical ResearchFormatos físicos adicionales: Printed edition:: Sin título; Printed edition:: Sin título; Printed edition:: Sin títuloClasificación CDD: 570.28 Clasificación LoC:QH324Recursos en línea: Libro electrónicoTexto
Contenidos:
Introduction -- Critique -- The Ideal Study -- What Can Go Wrong? -- Does It Really Go Wrong? -- The Consequences -- Construction -- Summary and Conclusions.
En: Springer Nature eBookResumen: This book examines animal research conducted with the goal of medical translation to humans. It is written by Dr. Bradley Weiner, a surgeon who is active at a high level clinically and in biomedical research. After documenting that the vast majority of biomedical animal research fails to result in benefits to humans via translation, the book examines the sources of such failure; including the failure to justify the use of animals, the failure to properly apply scientific methods, the failure to perform the research properly in the lab, the failure to consider the possibility of translation a priori, and systematic sources of failure built into the biomedical research enterprise. The book then explores options to improve the situation, for the benefit of both the animals and humans.
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Introduction -- Critique -- The Ideal Study -- What Can Go Wrong? -- Does It Really Go Wrong? -- The Consequences -- Construction -- Summary and Conclusions.

This book examines animal research conducted with the goal of medical translation to humans. It is written by Dr. Bradley Weiner, a surgeon who is active at a high level clinically and in biomedical research. After documenting that the vast majority of biomedical animal research fails to result in benefits to humans via translation, the book examines the sources of such failure; including the failure to justify the use of animals, the failure to properly apply scientific methods, the failure to perform the research properly in the lab, the failure to consider the possibility of translation a priori, and systematic sources of failure built into the biomedical research enterprise. The book then explores options to improve the situation, for the benefit of both the animals and humans.

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