TY  - BOOK
AU  - Golen,Kenneth
ED  - SpringerLink (Online service)
TI  - The Rho GTPases in Cancer
SN  - 9781441911117
AV  - RC261-271 
U1  - 614.5999 23
PY  - 2010///
CY  - New York, NY
PB  - Springer New York
KW  - Medicine
KW  - Oncology
KW  - Toxicology
KW  - Cytology
KW  - Biomedicine
KW  - Cancer Research
KW  - Cell Biology
KW  - Pharmacology/Toxicology
N1  - An Overview of the Rho GTPases -- Overview of Rho GTPase History -- Rho Proteins in Cancer -- The Rho Regulatory Proteins in Cancer -- RhoGDIs in Cancer -- Signaling through Galpha12/13 and RGS-RhoGEFs -- Vav Proteins in Cancer -- Rho GTPase-Activating Proteins in Cancer -- The Rho GTPase Proteins and Cancer -- RhoBTB Proteins in Cancer -- RhoC GTPase in Cancer Progression and Metastasis -- RhoB GTPase and FTIs in Cancer -- Regulation of Rho GTPase Activity Through Phosphorylation Events: A Brief Overview -- The Rho-Regulated ROCK Kinases in Cancer
N2  - The Rho GTPases in Cancer is the first volume to collect and summarize the current understanding of the Rho GTPases and their involvement in the progression of human cancer. The critical role of the Rho GTPases, their regulatory proteins, and their effectors in cancer progression has become increasingly evident over the past decade. As translational research increases on these proteins, their importance as keystone molecules in vital cellular process is highlighted. Thus, these molecules represent a major class of potential therapeutic targets that could be exploited clinically. This aspect of Rho GTPase biology is developing, therefore the contents of The Rho GTPases in Cancer should prove of interest to clinicians and members of the cancer research community wishing to develop new treatments for cancer
UR  - http://148.231.10.114:2048/login?url=http://link.springer.com/book/10.1007/978-1-4419-1111-7
ER  -