TY  - BOOK
AU  - Zakhari,Samir
AU  - Vasiliou,Vasilis
AU  - Guo,Q.Max
ED  - SpringerLink (Online service)
TI  - Alcohol and Cancer
SN  - 9781461400400
AV  - RC261-271 
U1  - 614.5999 23
PY  - 2011///
CY  - New York, NY
PB  - Springer New York
KW  - Medicine
KW  - Oncology
KW  - Toxicology
KW  - Biomedicine
KW  - Cancer Research
KW  - Pharmacology/Toxicology
N1  - Alcohol as a Human Carcinogen -- Overview of Tumorigenesis -- Alcohol and Cancer Epidemiology -- Alcohol Metabolism and Its Implications for Cancer -- Epigenetics, Alcohol, and Cancer.-  Alcohol, Cancer Genes, and Signaling Pathways.- Alcohol, Retinoic Acid, and Cancer -- Alcohol, Altered Protein Homeostasis, and Cancer -- Alcohol and the Inflammatory Function of Immune Cells in Cancer Development -- Immune Surveillance and Tumor Evasion -- Stem Cells and Alcohol-related Cancers -- Epilogue, Consensus Recommendations - Alcohol and Cancer
N2  - The World Health Organization has identified chronic alcohol consumption as one of the top ten risk factors for worldwide burden of disease. The International Agency for Research on Cancer has identified alcohol as carcinogenic to humans, including cancers of the upper aerodigestive tract, colon, liver and breast. Alcohol’s actions may be direct e.g. effects on retinoic acid and one-carbon metabolism, or indirect, through metabolites such as acetaldehyde and reactive oxygen species or through various signaling pathways that influence cell cycle and apoptosis that may contribute to carcinogenesis. This volume reviews the state of the art in alcohol-related cancer research in ten chapters
UR  - http://148.231.10.114:2048/login?url=http://link.springer.com/book/10.1007/978-1-4614-0040-0
ER  -