TY - BOOK AU - Hayward,Matthew M. ED - SpringerLink (Online service) TI - Lead-Seeking Approaches T2 - Topics in Medicinal Chemistry, SN - 9783642010750 AV - RS400-431 U1 - 615.19 23 PY - 2010/// CY - Berlin, Heidelberg PB - Springer Berlin Heidelberg KW - Chemistry KW - Neurosciences KW - Chemistry, Organic KW - Biochemistry KW - Medicinal Chemistry KW - Organic Chemistry N1 - Hit Triage: Medicinal Chemistry Strategies to Improve the Odds of Success in Discovery -- Lead Identification -- Lead Discovery Using Virtual Screening -- Overview of Hit to Lead: The Medicinal Chemist's Role from HTS Retest to Lead Optimization Hand Off -- NMR Spectroscopy in Fragment Based Drug Design -- High Throughput Screening in the Twenty-First Century N2 - Christopher A. Lipinski: Overview of Hit to Lead: The Medicinal Chemist’s Role from HTS Retest to Lead Optimization Hand Off Jeff W. Paslay • John E. Morin • Richard K. Harrison: High Throughput Screening in the Twenty - First Century Jack Andrew Bikker • Lakshmi S.Narasimhan: Lead Discovery Using Virtual Screening Maurizio Pellecchia: NMR Spectroscopy in Fragment Based Drug Design Kevin D. Freeman-Cook • Daniel W. Kung: Hit Triage – Medicinal Chemistry Strategies to Improve the Odds of Success in Discovery John W. Ellingboe • Adam M. Gilbert: Lead Identification UR - http://148.231.10.114:2048/login?url=http://link.springer.com/book/10.1007/978-3-642-01075-0 ER -