TY  - BOOK
AU  - Verma,Ashish S.
AU  - Singh,Anchal
TI  - Animal biotechnology: models in discovery and translation 
SN  - 9780123914347
AV  - RB125 
U1  - 660.6 23
PY  - 2014///
CY  - Amsterdam
PB  - Elsevier/Academic Press
KW  - Diseases
KW  - Animal models
KW  - Animal biotechnology
KW  - Biomedical engineering
KW  - Genetic engineering
KW  - Human-animal relationships
KW  - Disease Models, Animal
KW  - Biomedical Engineering
KW  - Biotechnology
KW  - Genetic Engineering
KW  - SCIENCE
KW  - Chemistry
KW  - Industrial & Technical
KW  - bisacsh
KW  - TECHNOLOGY & ENGINEERING
KW  - Chemical & Biochemical
KW  - fast
KW  - Electronic books
N1  - Includes bibliographical references and index; Cover image; Title page; Table of Contents; Copyright; Dedication; Contributors; Foreword; Preface; Acknowledgments; Section I: Human Diseases: In Vivo and In Vitro Models; Chapter 1. Drosophila: A Model for Biotechnologists; Abstract; Acknowledgments; Summary; What You Can Expect to Know; History and Methods; History; Principle; Methodology; Ethical Issues; Translational Significance; Drosophila Models of Human Disease; Drosophila-Based Therapeutic Peptide Production; World Wide Web Resources; References; Further Reading; Glossary; Abbreviations; Long Answer Questions; Short Answer Questions; Answers to Short Answer QuestionsChapter 2. Animal Models of Tuberculosis; Abstract; Summary; What You Can Expect to Know; History and Methods; Comparative Pathology of TB in Humans and Animals; Pathogen Diversity: Crossing Species Barriers; Host Diversity: Fundamental Processes and Fine Tuning; Animal Models of TB: Limits and Lessons; Various Animal Models; Ethical Issues; Translational Significance; World Wide Web Resources; Protocols; References; Further Reading; Glossary; Abbreviations; Long Answer Questions; Short Answer Questions; Answers to Short Answer Questions; Chapter 3. Animal Models for Neurodegenerative DisordersAbstract; Acknowledgments; Summary; What You Can Expect to Know; History and Methods; Principles; Methodology; Examples and Their Applications; Ethical Issues; Translational Significance; World Wide Web Resources; References; Further Reading; Glossary; Abbreviations; Long Answer Questions; Short Answer Questions; Answers to Short Answer Questions; Chapter 4. Epigenetics and Animal Models: Applications in Cancer Control and Treatment; Abstract; Summary; What You Can Expect to Know; History and Methods; History: Landscape of Epigenetics; PrincipleMethodology; Protocols; Ethical Issues; Translational Significance; World Wide Web Resources; References; Further Reading; Glossary; Abbreviations; Long Answer Questions; Short Answer Questions; Answers to Short Answer Questions; Chapter 5. Development of Mouse Models for Cancer Research; Abstract; Summary; What You Can Expect to Know; History and Methods; History; Principle; Methodology; Examples with Applications; Checklist for a Successful in vivo Experiment; Protocols; Ethical Issues; Translational Significance; World Wide Web Resources; References; Further Reading; Glossary; AbbreviationsLong Answer Questions; Short Answer Questions; Answers to Short Answer Questons; Chapter 6. Human Papillomavirus (HPV): Diagnosis and Treatment; Abstract; Summary; What You Can Expect to Know; History and Methods; Classification of Cancer; Cancer-Causing Agents; Cervical Cancer; Prevalence and Epidemiology of Cervical Cancer; Ethical Issues; Public Health Concerns About Vaccine Implementation; Treatment; Translational Significance; Therapeutic HPV Vaccines; Genetic-Based DNA Vaccines; Issues/Unanswered Questions Associated with HPV Vaccines
N2  - Animal Biotechnology introduces applications of animal biotechnology and implications for human health and welfare. It begins with an introduction to animal cell cultures and genome sequencing analysis and provides readers with a review of available cell and molecular tools. Topics here include the use of transgenic animal models, tissue engineering, nanobiotechnology, and proteomics. The book then delivers in-depth examples of applications in human health and prospects for the future, including cytogenetics and molecular genetics, xenografts, and treatment of HIV and cancers. All this is complemented by a discussion of the ethical and safety considerations in the field. Animal biotechnology is a broad field encompassing the polarities of fundamental and applied research, including molecular modeling, gene manipulation, development of diagnostics and vaccines, and manipulation of tissue. Given the tools that are currently available and the translational potential for these studies, animal biotechnology has become one of the most essential subjects for those studying life sciences. Highlights the latest biomedical applications of genetically modified and cloned animals with a focus on cancer and infectious diseasesProvides firsthand accounts of the use of biotechnology tools, including molecular markers, stem cells, and tissue engineering
UR  - http://148.231.10.114:2048/login?url=http://www.sciencedirect.com/science/book/9780124160026
ER  -