TY - BOOK AU - Sherbet,G.V. TI - Therapeutic strategies in cancer biology and pathology T2 - Elsevier insights SN - 9780124165908 AV - RC268.4 U1 - 616.99/4 23 PY - 2013/// CY - Amsterdam PB - Elsevier KW - Cancer KW - Molecular aspects KW - Genetic aspects KW - Treatment KW - Neoplasms KW - genetics KW - therapy KW - Genetic Therapy KW - methods KW - HEALTH & FITNESS KW - Diseases KW - General KW - bisacsh KW - MEDICAL KW - Clinical Medicine KW - Evidence-Based Medicine KW - Internal Medicine KW - fast KW - Electronic books KW - local N1 - Includes bibliographical references; RNA Interference in Genetic Regulation -- EMT Associated Gene Targeting -- Therapeutic Deployment of Metastasis-Associated Gene Function -- Genetic Determinants of Tumour and Metastasis Suppression -- Signalling and Transcription Regulators as Prospective Candidates in Cancer Therapy N2 - Currently, intensive effort is being directed toward the identification of molecular targets that can provide approaches to the development of novel therapeutic strategies in cancer management. This book focuses on metastasis-associated genes, metastasis promoter and suppressor genes, which relate specifically to behavioral alterations of cancer cells in epithelial mesenchymal transition, cancer stem cell maintenance and propagation, and to the acquisition of invasive and metastasis faculty. The function of these genes has implications for cell cycle regulation and cell proliferation and so constitute an essential element in cancer growth and dissemination UR - http://148.231.10.114:2048/login?url=http://www.sciencedirect.com/science/book/9780124165700 ER -