TY - BOOK AU - Suchmacher,Mendel AU - Geller,Mauro TI - Practical biostatistics: a user-friendly approach for evidence-based medicine SN - 9780124157941 AV - QH323.5 U1 - 570.15195 23 PY - 2012/// CY - Amsterdam, Boston PB - Elsevier/Academic Press KW - Biometry KW - Medical statistics KW - Medicine KW - Research KW - Statistical methods KW - methods KW - Data processing KW - Data Interpretation, Statistical KW - Mathematics KW - MATHEMATICS KW - Probability & Statistics KW - General KW - bisacsh KW - NATURE KW - Reference KW - SCIENCE KW - Life Sciences KW - Biology KW - fast KW - Biometrie KW - gnd KW - Biostatistik KW - Evidenz-basierte Medizin KW - Electronic books N1 - Includes bibliographical references and index; Part I : introduction. Study type determination -- Part II : observational studies. Determination of association strength between an exposure factor and an event in observational studies ; Increasing accuracy in observational studies -- Part III : step-by-step biostatistics of a clinical trial. Step 1 : investigator's hypothesis and expression of its corresponding outcome ; Step 2 : n estimation and n assessment of a published trial ; Step 3 : organization of variables and endpoints ; Step 4 : measures for results expression of a clinical trial ; Step 5 : determination of normality or non-normality of data distribution ; Step 6 : hypothesis testing ; Step 7 : correlating sample data with the general population 95% confidence interval -- Part IV : additional concepts in biostatistics. Individual and collective benefit and risk indexes inferable from intervention studies ; Statistical assessment of diagnostic tests for the clinic ; Systematic reviews and meta-analyses ; Correlation and regression ; Per protocol analysis and intention to treat analysis N2 - Evidence-based medicine aims to apply the best available evidence gained from the scientific method to medical decision making. It is a practice that uses statistical analysis of scientific methods and outcomes to drive further experimentation and diagnosis. The profusion of evidence-based medicine in medical practice and clinical research has produced a need for life scientists and clinical researchers to assimilate biostatistics into their work to meet efficacy and practical standards. Practical Biostatistics provides researchers, medical professionals, and students with a friendly, practical guide to biostatistics. With a detailed outline of implementation steps complemented by a review of important topics, this book can be used as a quick reference or a hands-on guide to effectively incorporate biostatistics in clinical trials UR - http://148.231.10.114:2048/login?url=http://www.sciencedirect.com/science/book/9780124157941 UR - http://148.231.10.114:2048/login?url=http://www.sciencedirect.com/science/book/9780124157941 ER -