TY  - BOOK
AU  - Focosi,Daniele
ED  - SpringerLink (Online service)
TI  - Resistance to Tyrosine Kinase Inhibitors
T2  - Resistance to Targeted Anti-Cancer Therapeutics,
SN  - 9783319460918
AV  - RC261-271 
U1  - 614.5999 23
PY  - 2016///
CY  - Cham
PB  - Springer International Publishing, Imprint: Springer
KW  - Medicine
KW  - Cancer research
KW  - Biomedicine
KW  - Cancer Research
N1  - Tyrosine Kinase Signaling Pathways in Normal and Cancer Cells -- Resistance to Tyrosine Kinase Inhibitors in different types of solid cancer -- The Resistance to Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia: An Overview -- Resistance to FLT3 Inhibitors -- Resistance to ALK inhibitors -- Resistance to Angiokinase Inhibitors -- Indications for Tyrosine Kinase Inhibitors in the Treatment of Solid Tumors
N2  - The volume will serve as a primer on tyrosine kinase signaling and its importance in cancer. The volume will first introduce the common denominators of small-molecule and antibody-derived inhibitors, as well as the general phenomenon of resistance. The volume will then detail resistance to the most commonly used classes of tyrosine kinase inhibitors, and will focus specific chapters on resistance to BCR-ABL1, FLT3, angiokinase family members, and ALK inhibitors
UR  - http://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-3-319-46091-8
ER  -