TY  - BOOK
AU  - Tseng,Fan-Gang
AU  - Santra,Tuhin Subhra
ED  - SpringerLink (Online service)
TI  - Essentials of Single-Cell Analysis: Concepts, Applications and Future Prospects 
T2  - Series in BioEngineering,
SN  - 9783662491188
AV  - R856-857 
U1  - 610.28 23
PY  - 2016///
CY  - Berlin, Heidelberg
PB  - Springer Berlin Heidelberg, Imprint: Springer
KW  - Engineering
KW  - Biotechnology
KW  - Bioinformatics
KW  - Cell biology
KW  - Biomedical engineering
KW  - Biomedical Engineering
KW  - Microengineering
KW  - Biological and Medical Physics, Biophysics
KW  - Cell Biology
N1  - Single Cell Behavioral Assays for Heterogeneity Studies -- Systems biology in single cells -- Electroporation for single cell analysis -- Microinjection for single cell analysis -- Optical tools for single cell manipulation and analysis -- Optoelectrokinetic manipulation for cell analysis -- Continuous micro/nano-fluidic devices for single cell analysis -- Single Cell Mechanical Properties: Label-Free Biomarkers for Cell Status Evaluation -- Cytometry of single cells for biology and biomedicine -- Single cell genomics and epigenomics -- Single cell Metabolomics -- Applications of cell based drug delivery systems: use of single cell assay -- Applications of Single Cell Sequencing in Cancer -- Single Cell Characterization of Microalgal Lipid Contents with Confocal Raman Microscopy -- Single Differentiated Neurons from Pluripotent Embryonic Stem Cells: Motor Protein Modelling and Neurodegenerative Disease
N2  - This book provides an overview of single-cell isolation, separation, injection, lysis and dynamics analysis as well as a study of their heterogeneity using different miniaturized devices. As an important part of single-cell analysis, different techniques including electroporation, microinjection, optical trapping, optoporation, rapid electrokinetic patterning and optoelectronic tweezers are described in detail. It presents different fluidic systems (e.g. continuous micro/nano-fluidic devices, microfluidic cytometry) and their integration with sensor technology, optical and hydrodynamic stretchers etc., and demonstrates the applications of single-cell analysis in systems biology, proteomics, genomics, epigenomics, cancer transcriptomics, metabolomics, biomedicine and drug delivery systems. It also discusses the future challenges for single-cell analysis, including the advantages and limitations. This book is enjoyable reading material while at the same time providing essential information to scientists in academia and professionals in industry working on different aspects of single-cell analysis. Dr. Fan-Gang Tseng is a Distinguished Professor of Engineering and System Science at the National Tsing Hua University, Taiwan. Dr. Tuhin Subhra Santra is a Research Associate at the California Nano Systems Institute, University of California at Los Angeles, USA
UR  - http://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-3-662-49118-8
ER  -