TY - BOOK AU - Malemud,Charles J. AU - Alsberg,Eben ED - SpringerLink (Online service) TI - Mesenchymal Stem Cells and Immunomodulation T2 - Stem Cell Biology and Regenerative Medicine, SN - 9783319467337 AV - QH588.S83 U1 - 571.6 23 PY - 2016/// CY - Cham PB - Springer International Publishing, Imprint: Springer KW - Life sciences KW - Immunology KW - Stem cells KW - Regenerative medicine KW - Tissue engineering KW - Life Sciences KW - Stem Cells KW - Regenerative Medicine/Tissue Engineering N1 - Overview -- Part I: Autoimmune Diseases -- Chapter 1: Altering Immune-Mediated Inflammatory Responses With Stem Cells -- Chapter 2: Rheumatoid Arthritis -- Chapter 3: Systemic Lupus Erythematosus -- Chapter 4: Crohn?s Diseases -- Chapter 5: Multiple Sclerosis -- Part II: Cancer -- Chapter 6: Eliminating Cancer with Stem Cells by Correcting Dysfunctional Immunity -- Chapter 7: Asymmetric Cell Division of Stem and Progenitor Cells in Homeostasis and Cancer -- Chapter 8: Stem Cells: Modifiers of Defective Transcription Factor Activity Induced by Cytokines in Cancer -- Chapter 9: Therapeutic Targeting of Prostate Cancer with Stem Cells -- Chapter 10: The Efficacy of Stem Cells in Experimental Animal Models of Leukemia -- Part III: Cardiovascular Disease -- Chapter 11: Immune-Mediated Inflammation in Heart Disease -- Chapter 12: Stem Cell Therapy: Dampening Immune-Mediated Inflammation in Coronary Artery Disease -- Part IV: Neurodegenerative Diseases -- Chapter 13: Similarities and Differences in Stem Cells Between Cancer, Normal and Injured Brain -- Chapter 2: Defective Immune Modulation in Parkinson?s Disease: Potential Role of Stem Cells -- Part V: Immune Modulation In Pregnancy and Parturition -- Chapter 14: Role of Immune-Mediated Inflammation in Pregnancy -- Chapter 15: Cytokine-Mediated Inflammation in Pre-Term Labor -- Chapter 16: Using Stem Cells to Prevent Inflammation-Induced Pre-Term Labor N2 - This essential volume explores mesenchymal stem cells (MSCs) and their potential to suppress immune-mediated inflammation. The chapters examine applications in autoimmune diseases such as lupus, rheumatoid arthritis and multiple sclerosis; blood cancers such as leukemia and lymphoma; and reproductive complications, specifically pre-term labor and use of MSCs in vitro and in animal models to discover methods of suppressing the causal inflammatory response. It also further defines the methodologies required to develop research on MSCs in vitro into established preclinical animal models including those which are proven replicas of autoimmunity and pre-term labor, to name but two. Mesenchymal Stem Cells and Immunomodulation, part of SpringerĀ“s Stem Cell Biology and Regenerative Medicine, is an invaluable resource for researchers and clinicians working with stem cells, autoimmune disease, oncology, and reproductive medicine UR - http://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-3-319-46733-7 ER -