TY  - BOOK
AU  - Ahmad,Aamir
AU  - Gadgeel,Shirish
ED  - SpringerLink (Online service)
TI  - Lung Cancer and Personalized Medicine: Current Knowledge and Therapies 
T2  - Advances in Experimental Medicine and Biology,
SN  - 9783319242231
AV  - RC261-271 
U1  - 614.5999 23
PY  - 2016///
CY  - Cham
PB  - Springer International Publishing, Imprint: Springer
KW  - Medicine
KW  - Cancer research
KW  - Molecular biology
KW  - Internal medicine
KW  - Oncology
KW  - Biomedicine
KW  - Cancer Research
KW  - Molecular Medicine
KW  - Internal Medicine
N1  - 1 Lung Cancer Statistics -- 2 Epidemiology of Lung Cancer -- 3 Lung Cancer In Never Smokers -- 4 Immune Therapy -- 5 Anti-angiogenesis in personalized therapy of lung cancer -- 6 Target therapy in Lung Cancer -- 7 Mechanisms of Resistance to EGFR Tyrosine Kinase Inhibitors and Therapeutic Approaches: an update -- 8 KRAS-Mutant Lung Cancers in the Era of Targeted Therapy -- 9 Anaplastic Lymphoma Kinase (ALK) Signaling in Lung Cancer -- 10 Chemotherapy Resistance in Lung Cancer -- 11 Current state of metal-based drugs for the efficient therapy of lung cancers and lung metastases
N2  - This, the first of two volumes on personalized medicine in lung cancer, touches on the core issues related to the understanding of lung cancer´statistics and epidemiology of lung cancer?along with the incidence of lung cancer in non-smokers. A major focus of this volume is the state of current therapies against lung cancer?immune, targeted therapies against EGFR TKIs, KRAS, ALK, angiogenesis; the associated challenges, especially resistance mechanisms; and recent progress in targeted drug development based on metal chemistry. Chapters are written by some of the leading experts in the field, who provide a better understanding of lung cancer, the factors that make it lethal, and current research focused on developing personalized treatment plans. With a unique mix of topics, this volume summarizes the current state-of-knowledge on lung cancer and the available therapies
UR  - http://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-3-319-24223-1
ER  -