TY - BOOK AU - Bunz,Fred ED - SpringerLink (Online service) TI - Principles of Cancer Genetics SN - 9789401774840 AV - RC261-271 U1 - 614.5999 23 PY - 2016/// CY - Dordrecht PB - Springer Netherlands, Imprint: Springer KW - Medicine KW - Cancer research KW - Human genetics KW - Oncology KW - Biomedicine KW - Cancer Research KW - Human Genetics N1 - Preface -- The Genetic Basis of Cancer -- Oncogenes -- Tumor Suppressor Genes -- Genetic Instability and Cancer -- Cancer Genomes.-Cancer Gene Pathways -- Genetic Alternations in Common Cancers -- Cancer Genetics in the Clinic -- Index N2 - This is the second edition of a widely used textbook that consolidates the basic concepts of the cancer gene theory and provides a framework for understanding the genetic basis of cancer. Particular attention is devoted to the origins of the mutations that cause cancer, and the application of evolutionary theory to explain how the cell clones that harbor cancer genes tend to expand. Focused on the altered genes and pathways that cause the growth of the most common tumors, Principles of Cancer Genetics is aimed at advanced undergraduates who have completed introductory coursework in genetics, biology and biochemistry, medical students and medical house staff. For students with a general interest in cancer, this book provides a highly accessible and readable overview. For more advanced students contemplating future study in the field of oncology and cancer research, this concise book will be useful as a primer UR - http://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-94-017-7484-0 ER -