TY  - BOOK
AU  - Karanasios,Eleftherios
AU  - Ktistakis,Nicholas T.
ED  - SpringerLink (Online service)
TI  - Autophagy at the Cell, Tissue and Organismal Level
T2  - SpringerBriefs in Cell Biology
SN  - 9783319331454
AV  - QH573-671 
U1  - 571.6 23
PY  - 2016///
CY  - Cham
PB  - Springer International Publishing, Imprint: Springer
KW  - Life sciences
KW  - Immunology
KW  - Biochemistry
KW  - Cell biology
KW  - Life Sciences
KW  - Cell Biology
KW  - Animal Biochemistry
N1  - Autophagy (Autophagia) from 1860 to 1963 -- History of Autophagy after 1963 -- Signalling in Autophagy -- Autophagosome Formation -- Physiological Role of Autophagy and Implications in Disease -- Studying autophagy: List of useful antibodies produced via a community effort
N2  - This book provides an expert summary of autophagy, a relatively new but rapidly expanding field of biomedical science with important implications in health and disease. After a historical review ranging up to the identification of autophagy genes in mammals, the authors discuss the signaling pathways that regulate autophagy, the mechanism of autophagosome formation and the physiological roles of autophagy in development, ageing, neurodegeneration, immune function and cell differentiation. A comprehensive list of useful antibodies for studying autophagy compiled as a community effort is included at the end. The book is intended for newcomers to the field, as well as more experienced researchers looking for a condensed but comprehensive introduction to the physiological function and regulation of the autophagic pathway in mammalian organisms
UR  - http://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-3-319-33145-4
ER  -