TY - BOOK AU - Van Dien,Stephen ED - SpringerLink (Online service) TI - Metabolic Engineering for Bioprocess Commercialization SN - 9783319419664 AV - QR1-502 U1 - 579 23 PY - 2016/// CY - Cham PB - Springer International Publishing, Imprint: Springer KW - Life sciences KW - Microbiology KW - Systems biology KW - Biology KW - Technique KW - Life Sciences KW - Applied Microbiology KW - Systems Biology KW - Biological Techniques N1 - Metabolic Engineering for Bioprocess Commercialization ? Introduction -- Gene Expression Engineering -- Heterologous pathway engineering -- Leveraging Gene Synthesis, Advanced Cloning Techniques, and Machine Learning for Metabolic Pathway Engineering -- Tolerance of microbial biocatalysts to feedstocks, products, and environmental conditions -- Biobased technology commercialization: The importance of lab to pilot scale-up N2 - This volume reviews the current metabolic engineering tools and technologies from a practical point of view, and guides researchers as they overcome challenges at various stages of organism and bioprocess development. Microbes have been engineered to produce a variety of industrial products such as fuels, basic chemicals, fine chemicals, nutritional supplements, and pharmaceutical intermediates, and new tools such as gene synthesis, advanced cloning techniques, ?omics? analysis, and mathematical modeling have greatly accelerated the pace of innovation in the field. Written by leading experts in the field from both academia and industry, key topics include synthetic biology, pathway engineering, metabolic flux manipulation, adaptive evolution, and fermentation process scale-up. It is suitable for non-specialists, and is a valuable resource for anyone embarking on the exciting path to harnessing the metabolic potential of microorganisms UR - http://148.231.10.114:2048/login?url=http://dx.doi.org/10.1007/978-3-319-41966-4 ER -