TY - BOOK AU - Weiner,Bradley K. ED - SpringerLink (Online service) TI - A Scientific Approach to Improving Animal Research in Biomedicine: Giving Animals a Chance SN - 9783031246777 AV - QH324 U1 - 570.28 23 PY - 2023/// CY - Cham PB - Springer International Publishing, Imprint: Springer KW - Biology KW - Technique KW - Animal welfare KW - Moral and ethical aspects KW - Medicine KW - Research KW - Experimental Organisms KW - Animal Ethics KW - Biomedical Research N1 - Acceso multiusuario; Introduction -- Critique -- The Ideal Study -- What Can Go Wrong? -- Does It Really Go Wrong? -- The Consequences -- Construction -- Summary and Conclusions N2 - This book examines animal research conducted with the goal of medical translation to humans. It is written by Dr. Bradley Weiner, a surgeon who is active at a high level clinically and in biomedical research. After documenting that the vast majority of biomedical animal research fails to result in benefits to humans via translation, the book examines the sources of such failure; including the failure to justify the use of animals, the failure to properly apply scientific methods, the failure to perform the research properly in the lab, the failure to consider the possibility of translation a priori, and systematic sources of failure built into the biomedical research enterprise. The book then explores options to improve the situation, for the benefit of both the animals and humans UR - http://libcon.rec.uabc.mx:2048/login?url=https://doi.org/10.1007/978-3-031-24677-7 ER -