TY  - BOOK
AU  - Bhat,Ajaz A.
AU  - Haris,Mohammad
AU  - Macha,Muzafar A.
AU  - Dhawan,Punita
ED  - SpringerLink (Online service)
TI  - Tight Junctions in Inflammation and Cancer
SN  - 9789819924158
AV  - QH573-671 
U1  - 571.6 23
PY  - 2023///
CY  - Singapore
PB  - Springer Nature Singapore, Imprint: Springer
KW  - Cytology
KW  - Cancer
KW  - Inflammation
KW  - Autoimmunity
KW  - Cell Biology
KW  - Cancer Biology
N1  - Acceso multiusuario; Chapter 1. Inflammation and Cancer: Role of Tight Junctions -- Chapter 2. Regulation of tight junction by cadherin adhesion and its implication in inflammation and cancer -- Chapter 3. Tight junctions, epithelial-mesenchymal transition and cancer metastasis -- Chapter 4. Imaging techniques to study tight junctions -- Chapter 5. Tight junction proteins as emerging drug targets: Expanding the horizons from inflammation to cancer -- Chapter 6. Tight Junctions and signaling pathways in cancer -- Chapter 7. Molecular architecture and function of tight junctions -- Chapter 8. The role of tight junction proteins in cancer
N2  - This book provides an updated account of tight junctions of different epithelia and endothelia and addresses their anatomy, biochemistry, physiology, synthesis, assembly, and modulation. It also discusses the relationship between molecular structure, function, regulation, posttranslational modifications of tight junction proteins and their role in gut microbiota maintenance, epithelial-mesenchymal transition, and intestinal barrier dysfunction-associated disorders important for the progression of human cancers. This book presents the pathological alterations of tight junctions at the blood-brain barrier that intensify or even initiate neurological dysfunction. Further, it reviews the significance of tight junctions and tight junction proteins in cancer development, infectious diseases, allergic reactions, and autoimmune disorders. Lastly, it highlights strategies for modulating tight junctions to enhance drug availability and organ deposition. This book is immensely useful for basic, translational, clinical, and interdisciplinary cancer researchers, practicing oncologists, and immunologists
UR  - http://libcon.rec.uabc.mx:2048/login?url=https://doi.org/10.1007/978-981-99-2415-8
ER  -