TY  - BOOK
AU  - Yi,Wen
ED  - SpringerLink (Online service)
TI  - Chemistry and Biology of O-GlcNAcylation
SN  - 9789819748648
AV  - R850.A1-854 
U1  - 610.72 23
PY  - 2024///
CY  - Singapore
PB  - Springer Nature Singapore, Imprint: Springer
KW  - Medicine
KW  - Research
KW  - Biology
KW  - Cytology
KW  - Biomedical Research
KW  - Cell Biology
N1  - Chapter 1. Chemical tools for decoding the functions of O-GlcNAcylation -- Chapter 2. Profiling O-GlcNAcylation with mass spectrometry -- Chapter 3. O-GlcNAcylation and cell metabolism -- Chapter 4. O-GlcNAcylation and transcriptional regulation and epigenetics -- Chapter 5. O-GlcNAcylation and signal transduction -- Chapter 6. O-GlcNAcylation and stem cells -- Chapter 7. O-GlcNAcylation and immune regulation -- Chapter 8. O-GlcNAcylation and neuronal development, neurodegeneration and neurological disorders
N2  - O-linked N-acetylglucosamine (O-GlcNAc) is a prevalent post-translational modification of numerous intracellular proteins. This modification has recently emerged as a key regulator of various important biological processes, including gene transcription, stress response, metabolic homeostasis, and immune regulation. Given the critical role of O-GlcNAc in normal physiology, increasing evidence has now demonstrated that deregulation of O-GlcNAc is closely associated with the development and progression of various diseases, including neurodegeneration, cardiovascular disease, and cancer. This book provides a comprehensive overview of the current progress and understanding of this modification in biology, and likely provides new research directions in the future
UR  - http://libcon.rec.uabc.mx:2048/login?url=https://doi.org/10.1007/978-981-97-4864-8
ER  -