Non-coding RNA and the Reproductive System [recurso electrónico] / edited by Dagmar Wilhelm, Pascal Bernard.

Colaborador(es): Wilhelm, Dagmar [editor.] | Bernard, Pascal [editor.] | SpringerLink (Online service)Tipo de material: TextoTextoSeries Advances in Experimental Medicine and Biology ; 886Editor: Dordrecht : Springer Netherlands : Imprint: Springer, 2016Descripción: VII, 198 p. 26 illus. online resourceTipo de contenido: text Tipo de medio: computer Tipo de portador: online resourceISBN: 9789401774178Tema(s): Medicine | Medical genetics | Reproductive medicine | Developmental biology | Biomedicine | Gene Function | Developmental Biology | Reproductive MedicineFormatos físicos adicionales: Printed edition:: Sin títuloClasificación CDD: 611.01816 Clasificación LoC:RB155-155.8QH431Recursos en línea: Libro electrónicoTexto En: Springer eBooksResumen: This book provides an overview of the role and function of regulatory RNAs that lack protein-coding potential in key reproductive tissues. This includes the role of small interfering RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs). Through clear, detailed and comprehensive debate, international leading experts discuss the role these novel regulators in normal development of sexual dimorphisms, including the differentiation of ovaries and testes, the genital tract including prostate, epididymis and uterus, as well as mammary glands. In addition, particular attention is paid on their role in pathophysiological processes within the reproductive tract. The power of next generation sequencing has proved to be an invaluable tool to discover new non-coding RNAs. While the identification of non-coding RNA is relatively easy, analysing their function represents still a challenge today. In this book, authors present historical and conceptual background information, highlight the ways in which non-coding RNAs function is analysed and present their vision of the future research in their key research area.
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This book provides an overview of the role and function of regulatory RNAs that lack protein-coding potential in key reproductive tissues. This includes the role of small interfering RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs). Through clear, detailed and comprehensive debate, international leading experts discuss the role these novel regulators in normal development of sexual dimorphisms, including the differentiation of ovaries and testes, the genital tract including prostate, epididymis and uterus, as well as mammary glands. In addition, particular attention is paid on their role in pathophysiological processes within the reproductive tract. The power of next generation sequencing has proved to be an invaluable tool to discover new non-coding RNAs. While the identification of non-coding RNA is relatively easy, analysing their function represents still a challenge today. In this book, authors present historical and conceptual background information, highlight the ways in which non-coding RNAs function is analysed and present their vision of the future research in their key research area.

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