Genetics of Melanoma [recurso electrónico] / edited by Carlos A. Torres-Cabala, Jonathan L. Curry.

Colaborador(es): Torres-Cabala, Carlos A [editor.] | Curry, Jonathan L [editor.] | SpringerLink (Online service)Tipo de material: TextoTextoSeries Cancer GeneticsEditor: New York, NY : Springer New York : Imprint: Springer, 2016Descripción: XV, 288 p. 54 illus., 53 illus. in color. online resourceTipo de contenido: text Tipo de medio: computer Tipo de portador: online resourceISBN: 9781493935543Tema(s): Medicine | Cancer research | Human genetics | Molecular biology | Biomedicine | Human Genetics | Cancer Research | Molecular MedicineFormatos físicos adicionales: Printed edition:: Sin títuloClasificación CDD: 611.01816 | 599.935 Clasificación LoC:RB155-155.8QH431Recursos en línea: Libro electrónicoTexto
Contenidos:
Biology of Melanoma -- The Role of the Immune System and Immunoregulatory Mechanisms Relevant to Melanoma -- Epidemiology and Clinical Characteristics of Melanoma -- Pathology of Melanoma -- Inherited Gene Mutations in Melanoma -- The MAPK Pathway in Melanoma -- The PI3K-AKT Pathway in Melanoma -- Biomarker Analysis for BRAF, NRAS, KIT, and BAP-1 Expression in Melanoma -- Molecular Platforms in Melanoma Mutation Analysis -- Immunotherapy in Melanoma -- Molecular Targeted Therapy in Melanoma -- Dermatologic Toxicities to Melanoma Targeted Therapy.
En: Springer eBooksResumen: This book discusses the molecular, biological, pathological, and clinical aspects of melanoma, with special emphasis in the new concepts of melanoma genetics. A multidisciplinary group of experts in Genetics, Dermatology, Pathology, and Melanoma Medical Oncology contribute state-of-the-art knowledge in melanoma research and clinical management, not only exposing the current status of knowledge of the topics but also providing their personal experiences and ideas about the future and potential practical application of the genetic aspects of melanoma. During the last few years we have witnessed an impressive amount of discoveries in the field of melanoma genetics which have changed our approach in understanding the pathogenesis and treatment of this lethal disease. Genetics of Melanoma is a practical approach to melanoma genetic mechanisms and their application in the diagnosis and treatment of this malignancy. It is an essential source of updated information and a powerful tool for clinicians, pathologists, and basic scientists who wish to understand, apply, and investigate the multiple new aspects of melanoma genetics.
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Biology of Melanoma -- The Role of the Immune System and Immunoregulatory Mechanisms Relevant to Melanoma -- Epidemiology and Clinical Characteristics of Melanoma -- Pathology of Melanoma -- Inherited Gene Mutations in Melanoma -- The MAPK Pathway in Melanoma -- The PI3K-AKT Pathway in Melanoma -- Biomarker Analysis for BRAF, NRAS, KIT, and BAP-1 Expression in Melanoma -- Molecular Platforms in Melanoma Mutation Analysis -- Immunotherapy in Melanoma -- Molecular Targeted Therapy in Melanoma -- Dermatologic Toxicities to Melanoma Targeted Therapy.

This book discusses the molecular, biological, pathological, and clinical aspects of melanoma, with special emphasis in the new concepts of melanoma genetics. A multidisciplinary group of experts in Genetics, Dermatology, Pathology, and Melanoma Medical Oncology contribute state-of-the-art knowledge in melanoma research and clinical management, not only exposing the current status of knowledge of the topics but also providing their personal experiences and ideas about the future and potential practical application of the genetic aspects of melanoma. During the last few years we have witnessed an impressive amount of discoveries in the field of melanoma genetics which have changed our approach in understanding the pathogenesis and treatment of this lethal disease. Genetics of Melanoma is a practical approach to melanoma genetic mechanisms and their application in the diagnosis and treatment of this malignancy. It is an essential source of updated information and a powerful tool for clinicians, pathologists, and basic scientists who wish to understand, apply, and investigate the multiple new aspects of melanoma genetics.

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