Immune biology of allogeneic hematopoietic stem cell transplantation [recurso electrónico] : models in discovery and translation / edited by Gérard Socié and Bruce R. Blazar.

Colaborador(es): Socié, Gérard | Blazar, Bruce RTipo de material: TextoTextoDetalles de publicación: Amsterdam ; Boston : Elsevier/AP, 2013Descripción: 1 online resource (xviii, 518 pages) : illustrationsTipo de contenido: text Tipo de medio: computer Tipo de portador: online resourceISBN: 9780123914651 (electronic bk.); 0123914655 (electronic bk.)Tema(s): Hematopoietic stem cells -- Transplantation | Blood -- Diseases | Immunology | Graft versus host disease | Hematology | Hematopoietic Stem Cell Transplantation | Graft vs Host Disease -- immunology | Transplantation, Homologous -- immunology | Transplantation Immunology | Blood Physiological Phenomena | Hematologic Diseases -- diagnosis | MEDICAL -- Research | Blood -- Diseases | Graft versus host disease | Hematology | Hematopoietic stem cells -- Transplantation | ImmunologyGénero/Forma: Electronic books.Formatos físicos adicionales: Print version:: Immune biology of allogeneic hematopoietic stem cell transplantation.Clasificación CDD: 616.02774 Clasificación LoC:RM171.4Recursos en línea: Libro electrónico ScienceDirectTexto
Contenidos:
Chapter 1 -- Overview of the immune biology of allogeneic hematopoietic stem cell transplantation -- Chapter 2 -- The HLA system in hematopoietic stem cell transplantation -- Chapter 3 -- The impact of minor histocompatibility antigens in allogeneic stem cell transplantation -- Chapter 3 -- The impact of minor histocompatibility antigens in allogeneic stem cell transplantation -- Chapter 5 -- Immune rejection: the immune biology of allogeneic hematopoietic stem cell transplantation (from mice to humans) -- Chapter 5 -- Immune rejection: the immune biology of allogeneic hematopoietic stem cell transplantation (from mice to humans) -- Chapter 7 -- Tumor-associated antigens -- Chapter 8 -- Impact of the conditioning regimen -- Chapter 9 -- Antigen presentation and antigen-presenting cells in graft-versus-host disease -- Chapter 10 -- T-cell costimulation in graft-versus-host disease and graft-versus-leukemia effect -- Chapter 11 -- Th1/Th2 and Tc1/Tc2 cells: biology, experimental models and clinical translation -- Chapter 12 -- Natural CD4+CD25+FOXP3+ regulatory T cells in graft-versus-host disease -- Chapter 13 -- Role of Th17 cells and interleukin 17 in graft-versus-host disease and graft-versus-leukemia reactivity -- Chapter 14 -- B and T cells in chronic graft-versus-host disease and graft-versus-leukemia -- Chapter 15 -- Natural killer cells in graft-versus-host disease and graft-versus-leukemia -- Chapter 16 -- Cytokines in graft-versus-host disease and graft-versus-leukemia -- Chapter 17 -- Chemokines and graft-versus-host disease -- Chapter 18 -- Intracellular sensors of immunity and allogeneic hematopoietic stem cell transplantation -- Statistical considerations -- Chapter 20 -- The endothelium in graft-versus-host disease and graft-versus-leukemia -- Chapter 21 -- Looking toward the future: an individualized approach to allogeneic transplantation.
Resumen: This book provides clinical and scientific researchers with a deep understanding of the current research and the implications for translational practice. By providing an overview of immune biology of HSCT, an explanation of immune rejection and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemia (GVL) effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future.
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Existencias
Tipo de ítem Biblioteca actual Colección Signatura Copia número Estado Fecha de vencimiento Código de barras
Libro Electrónico Biblioteca Electrónica
Colección de Libros Electrónicos RM171.4 (Browse shelf(Abre debajo)) 1 No para préstamo 380469-2001

Includes bibliographical references and index.

This book provides clinical and scientific researchers with a deep understanding of the current research and the implications for translational practice. By providing an overview of immune biology of HSCT, an explanation of immune rejection and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemia (GVL) effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future.

Chapter 1 -- Overview of the immune biology of allogeneic hematopoietic stem cell transplantation -- Chapter 2 -- The HLA system in hematopoietic stem cell transplantation -- Chapter 3 -- The impact of minor histocompatibility antigens in allogeneic stem cell transplantation -- Chapter 3 -- The impact of minor histocompatibility antigens in allogeneic stem cell transplantation -- Chapter 5 -- Immune rejection: the immune biology of allogeneic hematopoietic stem cell transplantation (from mice to humans) -- Chapter 5 -- Immune rejection: the immune biology of allogeneic hematopoietic stem cell transplantation (from mice to humans) -- Chapter 7 -- Tumor-associated antigens -- Chapter 8 -- Impact of the conditioning regimen -- Chapter 9 -- Antigen presentation and antigen-presenting cells in graft-versus-host disease -- Chapter 10 -- T-cell costimulation in graft-versus-host disease and graft-versus-leukemia effect -- Chapter 11 -- Th1/Th2 and Tc1/Tc2 cells: biology, experimental models and clinical translation -- Chapter 12 -- Natural CD4+CD25+FOXP3+ regulatory T cells in graft-versus-host disease -- Chapter 13 -- Role of Th17 cells and interleukin 17 in graft-versus-host disease and graft-versus-leukemia reactivity -- Chapter 14 -- B and T cells in chronic graft-versus-host disease and graft-versus-leukemia -- Chapter 15 -- Natural killer cells in graft-versus-host disease and graft-versus-leukemia -- Chapter 16 -- Cytokines in graft-versus-host disease and graft-versus-leukemia -- Chapter 17 -- Chemokines and graft-versus-host disease -- Chapter 18 -- Intracellular sensors of immunity and allogeneic hematopoietic stem cell transplantation -- Statistical considerations -- Chapter 20 -- The endothelium in graft-versus-host disease and graft-versus-leukemia -- Chapter 21 -- Looking toward the future: an individualized approach to allogeneic transplantation.

Print version record.

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