000			02242cam a22004094a 4500
001			u297445
003			SIRSI
005			20160811203820.0
008			041109s2005 njua frb 001 0 eng d
010			_a 2004026635
020			_a1588293831 (alk. paper)
040			_aDNLM/DLC _cDLC _dDLC
042			_apcc
050		0	_aRS160 _bN38 2005
082	0	0	_a615/.321 _222
245	1	0	_aNatural products : _bdrug discovery and therapeutic medicine / _cedited by Lixin Zhang, Arnold L. Demain.
260			_aTotowa, N.J. : _bHumana Press, _cc2005.
300			_axiv, 382 p. : _bil. ; _c26 cm.
504			_aIncluye referencias bibliográficas e índice.
505	0		_aNatural products and drug discovery / Arnold L. Demain and Lixin Zhang -- Integrated approaches for discovering novel drugs from microbial natural products / Lixin Zhang -- Automated analyses of HPLC profiles of microbial extracts: a new tool for drug discovery screening / Jose R. Tormo and Juan B. Garcia -- Manipulating microbial metabolites for drug discovery and production / C. Richard Hutchinson -- Improving drug discovery from microorganisms / Chris M. Farnet and Emmanuel Zazopoulos -- Developments in strain improvement technology: evolutionary engineering of industrial microorganisms through gene, pathway, and genome shuffling / Stephen B. del Cardayr -- The discovery of anticancer drugs from natural sources / David J. Newman and Gordon M. Cragg -- Case studies in natural product optimization: novel antitumor agents derived from taxus brevifolia and catharanthus roseus / Jian Hong and Shu-Hui Chen --
650		0	_aPharmacognosy.
650	1	2	_aDrug Design.
650	2	2	_aBiological Factors _xtherapeutic use.
650	2	2	_aBiological Products _xtherapeutic use.
650	2	2	_aPharmacogenetics.
650		4	_aFarmacognosia.
650		4	_aDrogas _xPruebas.
650		4	_aFactores Biológicos _xUso terapéutico.
650		4	_aProductos biológicos _xUso terapéutico.
650		4	_aFarmacogenética.
700	1		_aZhang, Lixin, _cPh. D.
700	1		_aDemain, A. L. _q(Arnold L.), _d1927-
856	4	1	_3Table of contents _uhttp://www.loc.gov/catdir/toc/ecip053/2004026635.html
596			_a9
942			_cLIBRO
999			_c141719 _d141719