000			02835nam a22004575i 4500
001			u371544
003			SIRSI
005			20160812080134.0
007			cr nn 008mamaa
008			100721s2010 xxu| s |||| 0|eng d
020			_a9781441959683 _9978-1-4419-5968-3
040			_cMX-MeUAM
050		4	_aRC254-282
082	0	4	_a616.994 _223
100	1		_aTu, Shi-Ming. _eauthor.
245	1	0	_aOrigin of Cancers _h[recurso electrónico] : _bClinical Perspectives and Implications of a Stem-Cell Theory of Cancer / _cby Shi-Ming Tu.
264		1	_aBoston, MA : _bSpringer US, _c2010.
300			_aCCXXXVII, 237p. 29 illus., 15 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aCancer Treatment and Research, _x0927-3042 ; _v154
505	0		_aCancer Myths -- History of Cancer -- Origin of Cancer -- Stem Cells -- Stem Cells and Cancer -- Cancer Stem Cells -- Cancer Niche -- Ontogeny and Oncology -- Diagnosis and Prognosis -- Cancer Targets -- Heterogeneity of Cancer -- Metastasis -- Cancer Immunity -- Drug Resistance -- Paradigm Shifts -- Experimental Proof -- Clinical Implications -- Curing Cancer -- Epilogue.
520			_aThe theory of a stem-cell origin of cancer is neither ground breaking nor earth shattering. Many prominent investigators have established the foundation for this concept and performed the vital experiments to support its validity and merit. The purpose of this book is to illustrate how this theory may completely transform our current views and perspectives about cancer. It is anticipated that the variety of ramifications of a stem-cell origin of cancers will be embraced by the medical research community to bring new treatment modalities to the cancer patient. "The stem-cell theory of cancer has significant biologic and clinical consequences. Though components remain open to debate the fundamental observations are grounded in scientific experimentation. This text explains the conceptual aspects of cancer stem cells with an emphasis on the implications for our patients." - Steven T. Rosen, M.D. Series Editor
650		0	_aMedicine.
650		0	_aOncology.
650		0	_aHuman genetics.
650	1	4	_aMedicine & Public Health.
650	2	4	_aOncology.
650	2	4	_aCancer Research.
650	2	4	_aHuman Genetics.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781441959676
830		0	_aCancer Treatment and Research, _x0927-3042 ; _v154
856	4	0	_zLibro electrónico _uhttp://148.231.10.114:2048/login?url=http://link.springer.com/book/10.1007/978-1-4419-5968-3
596			_a19
942			_cLIBRO_ELEC
999			_c199424 _d199424