000			02946nam a22004095i 4500
001			u371663
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005			20160812080140.0
007			cr nn 008mamaa
008			110110s2010 xxu| s |||| 0|eng d
020			_a9781441964458 _9978-1-4419-6445-8
040			_cMX-MeUAM
050		4	_aR-RZ
082	0	4	_a610 _223
100	1		_aThany, Steeve Hervé. _eeditor.
245	1	0	_aInsect Nicotinic Acetylcholine Receptors _h[recurso electrónico] / _cedited by Steeve Hervé Thany.
264		1	_aNew York, NY : _bSpringer New York, _c2010.
300			_aXX, 118p. 21 illus. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v683
505	0		_aIdentification of Cholinergic Synaptic Transmission in the Insect Nervous System -- The Evolution of Pentameric Ligand-Gated Ion Channels -- Diversity of Insect Nicotinic Acetylcholine Receptor Subunits -- Identification of Critical Elements Determining Toxins and Insecticide Affinity, Ligand Binding Domains and Channel Properties -- Electrophysiological Studies and Pharmacological Properties of Insect Native Nicotinic Acetylcholine Receptors -- Characterisation of Insect Nicotinic Acetylcholine Receptors by Heterologous Expression -- Neonicotinoid Insecticides -- Ecotoxicity of Neonicotinoid Insecticides to Bees -- State of the Art on Insect Nicotinic Acetylcholine Receptor Function in Learning and Memory.
520			_aThe aim of this book is to summarize our understanding on the insect nicotinic acetylcholine receptors. This area of research received great impetus from the identification of the first subunit sequences to be used as neonicotinoid insecticide target sites. Although a book of this nature can provide the details only of commonly published results, it is hoped that it may provide a useful guide to the newcomer to the field as well as to point out some of the future challenges. For example, we need to determine the precise subunit nomenclature of insect nicotinic receptors. This nomenclature varies amongst species and this led to some of the early confusion that persists. We need to be precise in identifying the subunit composition of native insect nicotinic receptor subtypes, their functional properties and physiological roles.
650		0	_aMedicine.
650	1	4	_aBiomedicine.
650	2	4	_aBiomedicine general.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781441964441
830		0	_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v683
856	4	0	_zLibro electrónico _uhttp://148.231.10.114:2048/login?url=http://link.springer.com/book/10.1007/978-1-4419-6445-8
596			_a19
942			_cLIBRO_ELEC
999			_c199543 _d199543