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008 101120s2011 xxu| s |||| 0|eng d
020 _a9781441974099
_9978-1-4419-7409-9
040 _cMX-MeUAM
050 4 _aRC321-580
082 0 4 _a612.8
_223
100 1 _aGjedde, Albert.
_eauthor.
245 1 0 _aNeurokinetics
_h[recurso electrónico] :
_bThe Dynamics of Neurobiology in Vivo /
_cby Albert Gjedde, William R. Bauer, Dean F. Wong.
264 1 _aBoston, MA :
_bSpringer US,
_c2011.
300 _aXVI, 343 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _a1: Introduction to Compartmental Analysis -- 2: Fundamentals of Compartmental Kinetics -- 3: Principles of Neuroreceptor Mapping in Vivo -- 4: Neuroreceptor Mapping in Vivo: Monoamines -- 5: Blood-Brain Transfer and Metabolism of Oxygen -- 6: Blood-Brain Glucose Transfer -- 7: Metabolism of Glucose -- 8: Brain Energy Metabolism -- 9: Glossary -- 10: References.
520 _aNeurokinetics: The Dynamics of Neurobiology in Vivo summarizes 20 years of work on the kinetics of blood-brain transfer and metabolism mechanisms in mammalian brain. The substances affiliated with these mechanisms include glucose, amino acids, monocarboxylic acids, and oxygen. These substances are important to energy metabolism and neurotransmission in the mammalian brain at rest and during activation. Neurokinetics: The Dynamics of Neurobiology in Vivo is divided in eight major chapters covering compartmental analysis, kinetic analysis of transport and metabolism, blood-brain transfer and metabolism of glucose, amino acids and oxygen, and amino acid metabolism and interaction of amino acid metabolites with receptors. This book is suitable for neuroscientists, physiologists, physicists, and medical scientists involved in the study of dynamic brain functions by means of brain imaging techniques (PET and fMRI) involved in the study of blood flow, blood-brain transfer, and metabolism. About the Authors: Dr. Albert Gjedde is Professor and Chairman at the Department of Neuroscience and Pharmacology at the University of Copenhagen. He previously served as director of neuroimaging laboratories in Aarhus, Denmark, and Montreal, Canada. In Denmark, Albert Gjedde founded three brain research centers; the PET-center of Aarhus University Hospitals, the Center of Functionally Integrative Neuroscience of Aarhus University, and the Danish Neuroscience Center of Aarhus University. Dr. Gjedde holds adjunct professorships at McGill University, Aarhus University, and Johns Hopkins University. His research interest is the dynamics of neurotransmission and brain energy metabolism. Dr. William R. Bauer is a mathematician and analyst. His expertise is in applied mathematics and related disciplines. He is a consultant to the Department of Radiology at Johns Hopkins University, specializing in algorithm development and techniques for estimating physiological parameters from PET data. Dr. Dean F. Wong is Professor of Radiology, Psychiatry, Neuroscience and Environmental Health Sciences, Vice-Chair of Radiology Administration and Training at Johns Hopkins University, and Director of the Section of High Resolution Brain PET (HRRT) Imaging within Nuclear Medicine/Radiology. His research involves the design, development, quantification, and application of radiopharmaceuticals imaged by positron emission tomography (PET) and single photon emission computed tomography (SPECT) for the study of in vivo brain chemistry dedicated to the study of neuropsychiatric disorders and their treatment using psychopharmacology.
650 0 _aMedicine.
650 0 _aHuman physiology.
650 0 _aNeurosciences.
650 0 _aRadiology, Medical.
650 0 _aBiochemistry.
650 1 4 _aBiomedicine.
650 2 4 _aNeurosciences.
650 2 4 _aBiophysics and Biological Physics.
650 2 4 _aMedical Biochemistry.
650 2 4 _aHuman Physiology.
650 2 4 _aNeuroradiology.
650 2 4 _aImaging / Radiology.
700 1 _aBauer, William R.
_eauthor.
700 1 _aWong, Dean F.
_eauthor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781441974082
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=http://link.springer.com/book/10.1007/978-1-4419-7409-9
596 _a19
942 _cLIBRO_ELEC
999 _c199798
_d199798