000			03216nam a22005415i 4500
001			u373175
003			SIRSI
005			20160812084133.0
007			cr nn 008mamaa
008			100715s2010 gw | s |||| 0|eng d
020			_a9783540692645 _9978-3-540-69264-5
040			_cMX-MeUAM
050		4	_aRB155-155.8
050		4	_aQH431
082	0	4	_a611.01816 _223
082	0	4	_a599.935 _223
100	1		_aLin, Shili. _eauthor.
245	1	0	_aHandbook on Analyzing Human Genetic Data _h[recurso electrónico] : _bComputational Approaches and Software / _cby Shili Lin, Hongyu Zhao.
264		1	_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg, _c2010.
300			_bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aPopulation Genetics -- Haplotype Structure -- Linkage Analysis of Qualitative Traits -- Linkage Analysis of Quantitative Traits -- Markov Chain Monte Carlo Linkage Analysis Methods -- Population-Based Association Studies -- Family-Based Association Studies -- Haplotype Association Analysis -- Multiple Comparisons/Testing Issues -- Estimating the Absolute Risk of Disease Associated with Identified Mutations -- Processing Large-Scale, High-Dimension Genetic and Gene Expression Data.
520			_aThe discipline of statistical genetics is highly computational. Be it exact computational methods, simulation based, or a hybrid of the two, computational packages are indispensable tools and constant companions of researchers in the field. This handbook is intended to provide human geneticists and other biomedical researchers with guidance on selections of appropriate computational methods and software packages for their specific genetic problems. It may also be used by students and other learners as a reference in conjunction with a more theoretical and/or methodologically oriented text book. This book tries to strike a balance between methodological expositions and practical guidelines for software selections. Wherever possible, comparisons among competing methods and software are made to highlight the relative advantages and disadvantage of the approaches so that the readers can make informed choices to best match their specific needs.
650		0	_aMedicine.
650		0	_aHuman genetics.
650		0	_aBioinformatics.
650		0	_aGenetics _xMathematics.
650		0	_aMathematical statistics.
650		0	_aStatistics.
650	1	4	_aBiomedicine.
650	2	4	_aHuman Genetics.
650	2	4	_aStatistics for Life Sciences, Medicine, Health Sciences.
650	2	4	_aBioinformatics.
650	2	4	_aComputational Biology/Bioinformatics.
650	2	4	_aGenetics and Population Dynamics.
650	2	4	_aStatistical Theory and Methods.
700	1		_aZhao, Hongyu. _eauthor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783540692638
856	4	0	_zLibro electrónico _uhttp://148.231.10.114:2048/login?url=http://link.springer.com/book/10.1007/978-3-540-69264-5
596			_a19
942			_cLIBRO_ELEC
999			_c201055 _d201055