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020 _a9783642030222
_9978-3-642-03022-2
040 _cMX-MeUAM
050 4 _aQH505
082 0 4 _a571.4
_223
100 1 _aNölting, Bengt.
_eauthor.
245 1 0 _aMethods in Modern Biophysics
_h[recurso electrónico] /
_cby Bengt Nölting.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2010.
300 _aXVI, 273p. 287 illus.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aThe three-dimensional structure of proteins -- Liquid chromatography of biomolecules -- Mass spectrometry -- X-ray structural analysis -- Protein infrared spectroscopy -- Electron microscopy -- Scanning probe microscopy -- Biophysical nanotechnology -- Proteomics: high throughput protein functional analysis -- Ion mobility spectrometry -- -Value analysis -- Evolutionary computer programming -- Rapid partial protein ladder sequencing -- Surface labeling analysis of protein interactions -- Conclusions -- References.
520 _aIncorporating recent dramatic advances, this textbook presents a fresh and timely introduction to modern biophysical methods. An array of new, faster and higher-power biophysical methods now enables scientists to examine the mysteries of life at a molecular level. This innovative text surveys and explains the ten key biophysical methods, including those related to biophysical nanotechnology, scanning probe microscopy, X-ray crystallography, ion mobility spectrometry, mass spectrometry, proteomics, and protein folding and structure. Incorporating much information previously unavailable in tutorial form, Nölting employs worked examples and about 270 illustrations to fully detail the techniques and their underlying mechanisms. Methods in Modern Biophysics is written for advanced undergraduate and graduate students, postdocs, researchers, lecturers, and professors in biophysics, biochemistry and related fields. Special features in the 3rd edition: Introduces rapid partial protein ladder sequencing - an important method for fast and highly sensitive identification of proteins, describes the determination of interaction surfaces in protein complexes by mass spectrometric mapping of binding of chemical linkers - a method to support the high-resolution structural analysis of large macromolecular assemblies.
650 0 _aPhysics.
650 0 _aBiotechnology.
650 0 _aChemistry, Physical organic.
650 0 _aMedicine.
650 0 _aBiochemistry.
650 0 _aBioinformatics.
650 1 4 _aPhysics.
650 2 4 _aBiophysics and Biological Physics.
650 2 4 _aBiotechnology.
650 2 4 _aBiochemistry, general.
650 2 4 _aMedicine/Public Health, general.
650 2 4 _aPhysical Chemistry.
650 2 4 _aBioinformatics.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642030215
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=http://link.springer.com/book/10.1007/978-3-642-03022-2
596 _a19
942 _cLIBRO_ELEC
999 _c201376
_d201376