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008 110117s2011 gw | s |||| 0|eng d
020 _a9783642137815
_9978-3-642-13781-5
040 _cMX-MeUAM
050 4 _aRC254-282
082 0 4 _a616.994
_223
100 1 _aReaman, Gregory H.
_eeditor.
245 1 0 _aChildhood Leukemia
_h[recurso electrónico] :
_bA Practical Handbook /
_cedited by Gregory H. Reaman, Franklin O. Smith.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2011.
300 _aX, 336 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aPediatric Oncology,
_x1613-5318
505 0 _aPart 1: Genetics and the Epidemiology of Leukemia in Children: Epidemiology of Childhood Acute Leukemia -- Part 2: Biology of Pediatric Leukemia: Biology of Lymphoblastic Leukemia.-Biology of Acute Myeloid Leukemia -- Part 3: Treatment Considerations in Childhood Leukemia: Classification and Treatment of Acute Lymphoblastic Leukemia.-Acute Myeloid Leukemia -- Part 4: The Impact of Pharmacogenetics and Pharmacogenomics of Childhood Leukemia: Pharmacogenetics and Pharmacogenomics Considerations in the Biology and Treatment of Childhood Leukemia: -- Part 5: The Potential Role of Biologically Targeted Therapy for Childhood Leukemia: Promising Targeted Agents.-Strategies for New Agent Development and Clinical Trial Considerations -- Part 6: Late Effects of Leukemia and Its Therapy: 9. Late Sequelae in Children with Acute Lymphoblastic Leukemia: Impact on Long-term Survival and Quality of Life -- Acute Toxicities and Late Sequelae and Survivorship in children with AML: Impact of Allogeneic Stem Cell Transplant -- Part 7: Psychosocial Implications of Acute Leukemia Diagnosis and Treatment for Children and Families: Appreciation and the Interdisciplinary Management of the Psychosocial Impact of Leukemia on Children and Their Families -- Part 8: Global Strategies to Improve Leukemia Care and Outcome for Children: Improved Outcome for Children with Acute Leukemia: How to Address Global Disparities.-Part 9: Perspectives and Future Direction: Future Challenges and Opportunities to Improve Outcomes for Children with Leukemia.
520 _aThis book is a comprehensive and up-to-date compendium on all aspects of childhood acute lymphoblastic and acute myeloid leukemia, which together constitute the most frequent cancer in the pediatric age group. After introductory chapters on the epidemiology and biology of pediatric leukemia, treatment considerations are extensively reviewed, with emphasis on the use of risk-adjusted treatment approaches. Promising targeted agents are discussed, and strategies for the development of new agents are appraised. The late effects of leukemia and its therapy are then considered in depth, with due attention to management of the psychosocial impact of the disease. Finally, global strategies to improve leukemia care and outcome are reviewed, and future directions discussed. The authors are internationally recognized experts and offer a largely evidence-based consensus on etiology, biology, and treatment. This handbook has far-reaching applicability to the clinical diagnosis and management of pediatric leukemia and will prove invaluable to specialists, generalists, and trainees alike.
650 0 _aMedicine.
650 0 _aHematology.
650 0 _aOncology.
650 0 _aPediatrics.
650 1 4 _aMedicine & Public Health.
650 2 4 _aOncology.
650 2 4 _aHematology.
650 2 4 _aPediatrics.
700 1 _aSmith, Franklin O.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642137808
830 0 _aPediatric Oncology,
_x1613-5318
856 4 0 _zLibro electrónico
_uhttp://148.231.10.114:2048/login?url=http://link.springer.com/book/10.1007/978-3-642-13781-5
596 _a19
942 _cLIBRO_ELEC
999 _c202466
_d202466